The impact of obesity associated inflammation on postmenopausal breast cancer. Grant uri icon


  • Obesity increases the incidence, progression, and eventual mortality from breast cancer in postmenopausal women, yet the mechanisms that underlie this relationship remain poorly understood. Our lab has found that weight gain during the menopausal window plays a critical role in tumor promotion, and in this study we will investigate how the inflammatory response to this weight gain is involved. Identifying inflammatory changes that promote breast cancer during this time will permit the rational design of therapies targeting inflammation. By combining traditional cancer therapies with agents directed at inflammation and other obesity-related targets, we hope to significantly contribute to the control of obesity-related breast cancer.

date/time interval

  • 2018 - 2023