HR job title
- Professor
- Contact Info
- 1 979 845 1333
Fluckey, James Professor
Positions
My research focuses on mechanisms associated with protein turnover and glucoregulatory function in muscle and how these mechanisms may be altered by exercise, aging, obesity, diabetes or periods of microgravity.
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Overview
Publications
selected publications
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academic article
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Lee, C. W., Galvan, E., Lee, T. V., Chen, V., Bui, S., Crouse, S. F., ... Riechman, S. E.
(2023).
Low Intake of Choline Is Associated with Diminished Strength and Lean Mass Gains in Older Adults. The Journal of Frailty and Aging.
12(1), 78-83.
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Davis, A. R., Goodenough, C. G., Westerlind, K. C., Strange, R., Deaver, J. W., Ryan, P. J., Riechman, S. E., & Fluckey, J. D.
(2022).
Myokines derived from contracting skeletal muscle suppress anabolism in MCF7 breast cancer cells by inhibiting mTOR. Frontiers in Physiology.
13, 1033585.
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Uranga, S., O'Reilly, C. L., Lewis, M. H., Lpez, S. M., Nghiem, P. P., & Fluckey, J. D.
(2022).
Anabolic Characterization Of Immortalized Murine L6, And Canine Myok9 Skeletal Myotubes. Medicine and Science in Sports and Exercise.
54(9S), 391-391.
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Ryan, P. J., Riechman, S., & Fluckey, J. D.
(2022).
Exercise Conditioned Perfusate Slows Growth In Cultured Pancreatic Cancer Cells. Medicine and Science in Sports and Exercise.
54(9S), 606-606.
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Lim, S., Deaver, J. W., Rosa-Caldwell, M. E., Lee, D. E., Morena da Silva, F., Cabrera, A. R., ... Greene, N. P.
(2022).
Muscle miR-16 deletion results in impaired insulin sensitivity and contractile function in a sex-dependent manner. American Journal of Physiology: Endocrinology and Metabolism.
322(3), E278-E292.
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O'Reilly, C. L., Uranga, S., & Fluckey, J. D.
(2021).
Culprits or consequences: Understanding the metabolic dysregulation of muscle in diabetes. World Journal of Biological Chemistry.
12(5), 70-86.
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J Ryan, P., Riechman, S. E., Fluckey, J. D., & Wu, G.
(2021).
Interorgan Metabolism of Amino Acids in Human Health and Disease. Advances in Experimental Medicine and Biology.
1332, 129-149.
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Castillo, S., Yamamoto, F. Y., O'Reilly, C., Fluckey, J. D., & Gatlin, D. M.
(2021).
Use of deuterium oxide (2H2O) to assess muscle protein synthesis in juvenile red drum (Sciaenops ocellatus) fed complete, and valine-deficient diets. Amino Acids.
53(9), 1431-1439.
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Rosa-Caldwell, M. E., Brown, J. L., Perry, R. A., Shimkus, K. L., Shirazi-Fard, Y., Brown, L. A., ... Greene, N. P.
(2020).
Regulation of mitochondrial quality following repeated bouts of hindlimb unloading. 45(3), 264-274.
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Uranga, S., Deever, J., Bird, M., O'Reilly, C., Ryan, P., & Fluckey, J.
(2020).
Effect of Electrical Pulse Stimulation on Anabolic Signaling in L6 Myotubes. The FASEB Journal.
34(S1), 1-1.
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Deaver, J., Lopez, S., Nghiem, P., Sheffield-Moore, M., Riechman, S., & Fluckey, J.
(2020).
MCF7 Human Breast Cancer Cells Engineered to Stably Overexpress DEPTOR via CRISPR/Cas9 to Reduce Anabolic Capacity. The FASEB Journal.
34(S1), 1-1.
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Deaver, J. W., Lpez, S. M., Ryan, P. J., Nghiem, P. P., Riechman, S. E., & Fluckey, J. D.
(2020).
Regulation of cellular anabolism by mTOR: or how I learned to stop worrying and love translation. Sports Medicine and Health Science.
2(4), 195-201.
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Ryan, P. J., Deaver, J. W., Koo, S., Touissaint, L. G., & Fluckey, J. D.
(2019).
Elucidating the Role of DEPTOR in Cultured Glioblastoma Multiforme Cancer Cells. The FASEB Journal.
33(S1), lb604-lb604.
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Deaver, J. W., O'Reilly, C. L., Cross, K. M., & Fluckey, J. D.
(2019).
Skeletal Muscle Anabolic Response Following Incubation with Protein Kinase C Activator OAG. The FASEB Journal.
33(S1), lb657-lb657.
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Lawler, J. M., Garcia-Villatoro, E. L., Guzzoni, V., Hord, J. M., Botchlett, R., Holly, D., ... Talcott, S.
(2019).
Effect of combined fish oil & Curcumin on murine skeletal muscle morphology and stress response proteins during mechanical unloading. NUTRITION RESEARCH.
65, 17-28.
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Lee, T. V., Lee, C. W., Chen, V., Bui, S., Fluckey, J. D., & Riechman, S. E.
(2019).
The effects of hindlimb unloading versus dietary cholesterol and resistance training on rat skeletal muscle responses. Lipids in Health and Disease.
18(1), 3.
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Shimkus, K. L., Shirazi-Fard, Y., Wiggs, M. P., Ullah, S. T., Pohlenz, C., Gatlin, D. M., ... Fluckey, J. D.
(2018).
Responses of skeletal muscle size and anabolism are reproducible with multiple periods of unloading/reloading. Journal of Applied Physiology.
125(5), 1456-1467.
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Kuczmarski, J. M., Hord, J. M., Lee, Y., Guzzoni, V., Rodriguez, D., Lawler, M. S., ... Lawler, J. M.
(2018).
Effect of Eukarion-134 on Akt-mTOR signalling in the rat soleus during 7days of mechanical unloading. Experimental Physiology.
103(4), 545-558.
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Chen, V., Lee, C. W., Fluckey, J. D., & Riechman, S. E.
(2018).
Blood Lipid is Associated with Skeletal Muscle PPAR Protein Content after a 10-week Resistance Exercise Training. Medicine and Science in Sports and Exercise.
50(5S), 808-808.
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Lee, C. W., Galvan, E., Lee, T. V., Chen, V. C., Bui, S., Crouse, S. F., ... Riechman, S. E.
(2018).
The Effects of Choline Intake and Resistance Exercise Training on Strength Gains in Older Adults. Medicine and Science in Sports and Exercise.
50(5S), 82-82.
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Phillips, C. A., Cavinder, C. A., Sigler, D. H., & Fluckey, J. D.
(2017).
Effect of various levels of dietary starch on glycogen replenishment in the light working horse. Professional Animal Scientist.
33(6), 729-738.
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Lee, Y., Fluckey, J. D., Chakraborty, S., & Muthuchamy, M.
(2017).
Hyperglycemia- and hyperinsulinemia-induced insulin resistance causes alterations in cellular bioenergetics and activation of inflammatory signaling in lymphatic muscle. The FASEB Journal.
31(7), 2744-2759.
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Brown, J. L., Rosa-Caldwell, M. E., Lee, D. E., Brown, L. A., Perry, R. A., Shimkus, K. L., ... Greene, N. P.
(2017).
PGC-14 gene expression is suppressed by the IL-6-MEK-ERK 1/2 MAPK signalling axis and altered by resistance exercise, obesity and muscle injury. Acta Physiologica.
220(2), 275-288.
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Katsma, M. S., Patel, S. H., Eldon, E., Corbell, K. A., Shimkus, K. L., Fluckey, J. D., & Carroll, C. C.
(2017).
The influence of chronic IL-6 exposure, in vivo, on rat Achilles tendon extracellular matrix. Cytokine.
93, 10-14.
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Macias, B. R., Lima, F., Swift, J. M., Shirazi-Fard, Y., Greene, E. S., Allen, M. R., ... Bloomfield, S. A.
(2016).
Simulating the Lunar Environment: Partial Weightbearing and High-LET Radiation-Induce Bone Loss and Increase Sclerostin-Positive Osteocytes. RADIATION RESEARCH.
186(3), 254-263.
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Lee, D. E., Brown, J. L., Rosa, M. E., Brown, L. A., Perry, R. A., Wiggs, M. P., ... Greene, N. P.
(2016).
Cover Image, Volume 117, Number 8, August 2016. Journal of Cellular Biochemistry.
117(8), i-i.
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Lee, D. E., Brown, J. L., Rosa, M. E., Brown, L. A., Perry, R. A., Wiggs, M. P., ... Greene, N. P.
(2016).
microRNA-16 Is Downregulated During Insulin Resistance and Controls Skeletal Muscle Protein Accretion. Journal of Cellular Biochemistry.
117(8), 1775-1787.
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Simmons, E., Fluckey, J. D., & Riechman, S. E.
(2016).
Cumulative Muscle Protein Synthesis and Protein Intake Requirements. Annual Review of Nutrition.
36(1), 17-43.
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Galvan, E., Walker, D. K., Simbo, S. Y., Dalton, R., Levers, K., O'Connor, A., ... Kreider, R. B.
(2016).
Acute and chronic safety and efficacy of dose dependent creatine nitrate supplementation and exercise performance. Journal of the International Society of Sports Nutrition.
13(1), 12.
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Hudson, M. B., Smuder, A. J., Nelson, W. B., Wiggs, M. P., Shimkus, K. L., Fluckey, J. D., Szeto, H. H., & Powers, S. K.
(2015).
Partial Support Ventilation and Mitochondrial-Targeted Antioxidants Protect against Ventilator-Induced Decreases in Diaphragm Muscle Protein Synthesis. PLoS One.
10(9), e0137693-e0137693.
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Fluckey, J. D., Lambert, B. S., Greene, N. P., Shimkus, K. L., Cardin, J. M., Riechman, S. E., & Crouse, S. F.
(2015).
Reply to letter to the editor: to D2O or not to D2O? What are the reasons we D2O it at all?. American Journal of Physiology: Endocrinology and Metabolism.
308(10), E928-E931.
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Lambert, B. S., Shimkus, K. L., Fluckey, J. D., Riechman, S. E., Greene, N. P., Cardin, J. M., & Crouse, S. F.
(2015).
Anabolic responses to acute and chronic resistance exercise are enhanced when combined with aquatic treadmill exercise. American Journal of Physiology: Endocrinology and Metabolism.
308(3), E192-E200.
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Brown, J. L., Perry, R. A., Shimkus, K. L., Lee, D. E., Rosa, M. E., Cardin, J. M., ... Greene, N. P.
(2015).
Canonical Mitochondrial Biogenesis And Mitochondrial Translation Following Multiple Bouts Of Disuse. Medicine and Science in Sports and Exercise.
47(5S), 222-222.
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Lee, D., Brown, J. L., Rosa, M. E., Brown, L. A., Perry, R. A., Nilsson, M. I., ... Greene, N. P.
(2015).
microRNAs In Skeletal Muscle and Their Response to Resistance Exercise in Insulin Resistant Diabetes. Medicine and Science in Sports and Exercise.
47(5S), 190-190.
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Greene, N. P., Nilsson, M. I., Washington, T. A., Lee, D. E., Brown, L. A., Papineau, A. M., ... Fluckey, J. D.
(2014).
Impaired exercise-induced mitochondrial biogenesis in the obese Zucker rat, despite PGC-1 induction, is due to compromised mitochondrial translation elongation. American Journal of Physiology: Endocrinology and Metabolism.
306(5), E503-E511.
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Lambert, B. S., Greene, N. P., Carradine, A. T., Joubert, D. P., Fluckey, J. D., Riechman, S. E., & Crouse, S. F.
(2014).
Aquatic treadmill training reduces blood pressure reactivity to physical stress. Medicine and Science in Sports and Exercise.
46(4), 809-816.
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Kresta, J. Y., Oliver, J. M., Jagim, A. R., Fluckey, J., Riechman, S., Kelly, K., ... Kreider, R. B.
(2014).
Effects of 28days of beta-alanine and creatine supplementation on muscle carnosine, body composition and exercise performance in recreationally active females. Journal of the International Society of Sports Nutrition.
11(1), 55-15.
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Oliver, J. M., Jagim, A. R., Pischel, I., Jger, R., Purpura, M., Sanchez, A., ... Kreider, R. B.
(2014).
Effects of short-term ingestion of Russian Tarragon prior to creatine monohydrate supplementation on whole body and muscle creatine retention and anaerobic sprint capacity: a preliminary investigation. Journal of the International Society of Sports Nutrition.
11(1), 6.
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Boudreaux, R. D., Swift, J. M., Gasier, H. G., Wiggs, M. P., Hogan, H. A., Fluckey, J. D., & Bloomfield, S. A.
(2014).
Increased resistance during jump exercise does not enhance cortical bone formation. Medicine and Science in Sports and Exercise.
46(5), 982-989.
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Nilsson, M. I., Dobson, J. P., Greene, N. P., Wiggs, M. P., Shimkus, K. L., Wudeck, E. V., ... Fluckey, J. D.
(2013).
Abnormal protein turnover and anabolic resistance to exercise in sarcopenic obesity. The FASEB Journal.
27(10), 3905-3916.
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Oliver, J. M., Jagim, A. R., Sanchez, A. C., Mardock, M. A., Kelly, K. A., Meredith, H. J., ... Kreider, R. B.
(2013).
Greater gains in strength and power with intraset rest intervals in hypertrophic training. Journal of Strength and Conditioning Research.
27(11), 3116-3131.
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Greene, N. P., Fluckey, J. D., Lambert, B. S., Greene, E. S., Riechman, S. E., & Crouse, S. F.
(2012).
Regulators of blood lipids and lipoproteins? PPAR and AMPK, induced by exercise, are correlated with lipids and lipoproteins in overweight/obese men and women. American Journal of Physiology: Endocrinology and Metabolism.
303(10), E1212-E1221.
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Jagim, A. R., Oliver, J. M., Sanchez, A., Galvan, E., Fluckey, J., Riechman, S., ... Kreider, R. B.
(2012).
A buffered form of creatine does not promote greater changes in muscle creatine content, body composition, or training adaptations than creatine monohydrate. Journal of the International Society of Sports Nutrition.
9(1), 43.
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Gasier, H. G., Fluckey, J. D., Previs, S. F., Wiggs, M. P., & Riechman, S. E.
(2012).
Acute resistance exercise augments integrative myofibrillar protein synthesis. Metabolism: clinical and experimental.
61(2), 153-156.
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Gasier, H. G., Riechman, S. E., Wiggs, M. P., Buentello, A., Previs, S. F., & Fluckey, J. D.
(2011).
Cumulative responses of muscle protein synthesis are augmented with chronic resistance exercise training. Acta Physiologica.
201(3), 381-389.
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Swift, J. M., Gasier, H. G., Swift, S. N., Wiggs, M. P., Hogan, H. A., Fluckey, J. D., & Bloomfield, S. A.
(2010).
Increased training loads do not magnify cancellous bone gains with rodent jump resistance exercise. Journal of Applied Physiology.
109(6), 1600-1607.
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Nilsson, M. I., Greene, N. P., Dobson, J. P., Wiggs, M. P., Gasier, H. G., Macias, B. R., Shimkus, K. L., & Fluckey, J. D.
(2010).
Insulin resistance syndrome blunts the mitochondrial anabolic response following resistance exercise. American Journal of Physiology: Endocrinology and Metabolism.
299(3), E466-E474.
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Shimkus, K. L., Wiggs, M. P., Shirazi-Fard, Y., Hogan, H. A., & Fluckey, J. D.
(2010).
Effects of Multiple Bouts of Long-duration Hindlimb Unloading and Recovery on Rat Hindlimb Muscles. Medicine and Science in Sports and Exercise.
42(10), 64-64.
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Dobson, J. P., Nilsson, M. I., Wiggs, M. P., Gasier, H. G., & Fluckey, J. D.
(2010).
Elevations in Myofibrillar Protein Fractional Synthesis Rates Following 5-Weeks of Dynamic Resistance Exercise. Medicine and Science in Sports and Exercise.
42(10), 86-86.
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Gasier, H. G., Fluckey, J. D., & Previs, S. F.
(2010).
The application of 2H2O to measure skeletal muscle protein synthesis. Nutrition and Metabolism.
7(1), 31-31.
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Gasier, H. G., Riechman, S. E., Wiggs, M. P., Previs, S. F., & Fluckey, J. D.
(2009).
A comparison of 2H2O and phenylalanine flooding dose to investigate muscle protein synthesis with acute exercise in rats. American Journal of Physiology: Endocrinology and Metabolism.
297(1), E252-E259.
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Gasier, H. G., Previs, S. F., Pohlenz, C., Fluckey, J. D., Gatlin, D. M., & Buentello, J. A.
(2009).
A novel approach for assessing protein synthesis in channel catfish, Ictalurus punctatus. Comparative Biochemistry and Physiology B: Biochemistry and Molecular Biology.
154(2), 235-238.
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Greene, N. P., Nilsson, M. I., Lambert, B. S., Reichman, S. E., Fluckey, J. D., & Crouse, S. F.
(2009).
Changes In PPARd Protein Content Following Acute Aerobic Exercise In Human Vastus Lateralis Muscle. Medicine and Science in Sports and Exercise.
41(5), 78-78.
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Norrbrand, L., Fluckey, J. D., Pozzo, M., & Tesch, P. A.
(2008).
Resistance training using eccentric overload induces early adaptations in skeletal muscle size. European Journal of Applied Physiology.
102(3), 271-281.
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Wiggs, M. P., Jones, K. P., Rayburn, W. L., Davis, T., Dohm, G. L., & Fluckey, J. D.
(2007).
Insulin signaling in sedentary human skeletal muscle via PI3K is necessary for protein synthesis. The FASEB Journal.
21(6), lb119-lb120.
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Gasier, H. G., Wiggs, M. P., Swift, J. M., Oliphant, D. A., Riechman, S. A., & Fluckey, J. D.
(2007).
Plateau effects of resistance exercise result from overexpression of eIF4EBP1. The FASEB Journal.
21(6), lb119-lb119.
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Dupont-Versteegden, E. E., Strotman, B. A., Gurley, C. M., Gaddy, D., Knox, M., Fluckey, J. D., & Peterson, C. A.
(2006).
Nuclear translocation of EndoG at the initiation of disuse muscle atrophy and apoptosis is specific to myonuclei. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology.
291(6), R1730-R1740.
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Dupont-Versteegden, E. E., Fluckey, J. D., Knox, M., Gaddy, D., & Peterson, C. A.
(2006).
Effect of flywheel-based resistance exercise on processes contributing to muscle atrophy during unloading in adult rats. Journal of Applied Physiology.
101(1), 202-212.
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Fluckey, J. D., Knox, M., Smith, L., Dupont-Versteegden, E. E., Gaddy, D., Tesch, P. A., & Peterson, C. A.
(2006).
Insulin-facilitated increase of muscle protein synthesis after resistance exercise involves a MAP kinase pathway. American Journal of Physiology: Endocrinology and Metabolism.
290(6), E1205-E1211.
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Hays, N. P., Starling, R. D., Sullivan, D. H., Fluckey, J. D., Coker, R. H., Williams, R. H., & Evans, W. J.
(2006).
Effects of an ad libitum, high carbohydrate diet and aerobic exercise training on insulin action and muscle metabolism in older men and women. Journal of Gerontology Series A: Biological Sciences and Medical Sciences.
61(3), 299-304.
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Hays, N. P., Starling, R. D., Sullivan, D. H., Fluckey, J. D., Coker, R. H., & Evans, W. J.
(2006).
Comparison of insulin sensitivity assessment indices with euglycemic-hyperinsulinemic clamp data after a dietary and exercise intervention in older adults. Metabolism: clinical and experimental.
55(4), 525-532.
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Carroll, C. C., Fluckey, J. D., Williams, R. H., Sullivan, D. H., & Trappe, T. A.
(2005).
Human soleus and vastus lateralis muscle protein metabolism with an amino acid infusion. American Journal of Physiology: Endocrinology and Metabolism.
288(3), E479-E485.
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Fluckey, J. D., Dupont-Versteegden, E. E., Knox, M., Gaddy, D., Tesch, P. A., & Peterson, C. A.
(2004).
Insulin facilitation of muscle protein synthesis following resistance exercise in hindlimb-suspended rats is independent of a rapamycin-sensitive pathway. American Journal of Physiology: Endocrinology and Metabolism.
287(6), E1070-E1075.
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Knox, M., Fluckey, J. D., Bennett, P., Peterson, C. A., & Dupont-Versteegden, E. E.
(2004).
Hindlimb unloading in adult rats using an alternative tail harness design. Aviation, Space, and Environmental Medicine.
75(8), 692-696.
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Fluckey, J. D., Cortright, R. N., Tapscott, E., Koves, T., Smith, L., Pohnert, S., & Dohm, G. L.
(2004).
Active involvement of PKC for insulin-mediated rates of muscle protein synthesis in Zucker rats. American Journal of Physiology: Endocrinology and Metabolism.
286(5), E753-E758.
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Campbell, W. W., Haub, M. D., Fluckey, J. D., Ostlund, R. E., Thyfault, J. P., Morse-Carrithers, H., Hulver, M. W., & Birge, Z. K.
(2004).
Pinitol supplementation does not affect insulin-mediated glucose metabolism and muscle insulin receptor content and phosphorylation in older humans. The Journal of Nutrition.
134(11), 2998-3003.
-
Fluckey, J. D., Knox, M., Smith, L., Dupont-Versteegden, E. E., Gaddy, D., Tesch, P. A., & Peterson, C. A.
(2004).
The Insulin-Facilitated Increase of Muscle Protein Synthesis after Resistance Exercise Involves a MAP-Kinase Pathway. Medicine and Science in Sports and Exercise.
36(5), s183-s184.
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Hays, N. P., Starling, R. D., Liu, X., Sullivan, D. H., Trappe, T. A., Fluckey, J. D., & Evans, W. J.
(2004).
Effects of an ad libitum low-fat, high-carbohydrate diet on body weight, body composition, and fat distribution in older men and women: a randomized controlled trial. Archives of Internal Medicine.
164(2), 210-217.
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Trappe, S., Gallagher, P., Harber, M., Carrithers, J., Fluckey, J., & Trappe, T.
(2003).
Single muscle fibre contractile properties in young and old men and women. The Journal of Physiology.
552(Pt 1), 47-58.
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Wells, A. M., Haub, M. D., Fluckey, J., Williams, D. K., Chernoff, R., & Campbell, W. W.
(2003).
Comparisons of vegetarian and beef-containing diets on hematological indexes and iron stores during a period of resistive training in older men. Journal of the American Dietetic Association.
103(5), 594-601.
-
Fluckey, J. D., Dupont-Versteegden, E. E., Montague, D. C., Knox, M., Tesch, P., Peterson, C. A., & Gaddy-Kurten, D.
(2002).
A rat resistance exercise regimen attenuates losses of musculoskeletal mass during hindlimb suspension. Acta Physiol Scand.
176(4), 293-300.
-
Fluckey, J. D., Asp, S., Enevoldsen, L. H., & Galbo, H.
(2001).
Insulin action on rates of muscle protein synthesis following eccentric, muscle-damaging contractions. Acta Physiol Scand.
173(4), 379-384.
-
Trappe, T. A.
(2001).
Skeletal Muscle PGF2and PGE2 in Response to Eccentric Resistance Exercise: Influence of Ibuprofen and Acetaminophen. Journal of Clinical Endocrinology and Metabolism.
86(10), 5067-5070.
-
Trappe, T. A., Fluckey, J. D., White, F., Lambert, C. P., & Evans, W. J.
(2001).
Skeletal muscle PGF(2)(alpha) and PGE(2) in response to eccentric resistance exercise: influence of ibuprofen acetaminophen. Journal of Clinical Endocrinology and Metabolism.
86(10), 5067-5070.
-
Enevoldsen, L. H., Stallknecht, B., Fluckey, J. D., & Galbo, H.
(2000).
Effect of exercise training on in vivo lipolysis in intra-abdominal adipose tissue in rats. American Journal of Physiology: Endocrinology and Metabolism.
279(3 42-3),
-
Enevoldsen, L. H., Stallknecht, B., Fluckey, J. D., & Galbo, H.
(2000).
Effect of exercise training on in vivo lipolysis in intra-abdominal adipose tissue in rats. American Journal of Physiology: Endocrinology and Metabolism.
279(3), E585-E592.
-
Fluckey, J. D., Pohnert, S. C., Boyd, S. G., Cortright, R. N., Trappe, T. A., & Dohm, G. L.
(2000).
Insulin stimulation of muscle protein synthesis in obese Zucker rats is not via a rapamycin-sensitive pathway. American Journal of Physiology: Endocrinology and Metabolism.
279(1 42-1),
-
Fluckey, J. D., Pohnert, S. C., Boyd, S. G., Cortright, R. N., Trappe, T. A., & Dohm, G. L.
(2000).
Insulin stimulation of muscle protein synthesis in obese Zucker rats is not via a rapamycin-sensitive pathway. American Journal of Physiology: Endocrinology and Metabolism.
279(1 42-1),
-
Fluckey, J. D., Pohnert, S. C., Boyd, S. G., Cortright, R. N., Trappe, T. A., & Dohm, G. L.
(2000).
Insulin stimulation of muscle protein synthesis in obese Zucker rats is not via a rapamycin-sensitive pathway. American Journal of Physiology: Endocrinology and Metabolism.
279(1), E182-E187.
-
Hernandez, J. M., Moccia, T., Fluckey, J. D., Ulbrecht, J. S., & Farrell, P. A.
(2000).
Fluid snacks to help persons with type 1 diabetes avoid late onset postexercise hypoglycemia. Medicine and Science in Sports and Exercise.
32(5), 904-910.
-
Enevoldsen, L. H., Stallknecht, B., Fluckey, J. D., & Galbo, H.
(2000).
Effect of exercise training on in vivo insulin-stimulated glucose uptake in intra-abdominal adipose tissue in rats. American Journal of Physiology: Endocrinology and Metabolism.
278(1 41-1),
-
Enevoldsen, L. H., Stallknecht, B., Fluckey, J. D., & Galbo, H.
(2000).
Effect of exercise training on in vivo insulin-stimulated glucose uptake in intra-abdominal adipose tissue in rats. American Journal of Physiology: Endocrinology and Metabolism.
278(1), E25-E34.
-
Fluckey, J. D., Ploug, T., & Galbo, H.
(1999).
Attenuated insulin action on glucose uptake and transport in muscle following resistance exercise in rats. Acta Physiol Scand.
167(1), 77-82.
-
Farrell, P. A., Fedele, M. J., Hernandez, J., Fluckey, J. D., Miller, J. L., Lang, C. H., ... Jefferson, L. S.
(1999).
Hypertrophy of skeletal muscle in diabetic rats in response to chronic resistance exercise. Journal of Applied Physiology.
87(3), 1075-1082.
-
Fluckey, J. D., Ploug, T., & Galbo, H.
(1999).
Mechanisms associated with hypoxia- and contraction-mediated glucose transport in muscle are fibre-dependent. Acta Physiol Scand.
167(1), 83-87.
-
Stallknecht, B., Donsmark, M., Enevoldsen, L. H., Fluckey, J. D., & Galbo, H.
(1999).
Estimation of rat muscle blood flow by microdialysis probes perfused with ethanol, [14C]ethanol, and 3H2O. Journal of Applied Physiology.
86(3), 1054-1061.
-
Fedele, M. J., Fluckey, J. D., Hernandez, J. M., Vary, T. C., Kimball, S. R., Jefferson, L. S., & Farrell, P. A.
(1999).
REDUCED SKELETAL MUSCLE MASS IN MODERATELY DIABETIC RATS IS PARTIALLY RESTORED BY RESISTANCE EXERCISE. Medicine and Science in Sports and Exercise.
31(5), s267-S267.
-
Cortright, R. N., Zheng, D. H., Jones, J. P., Fluckey, J. D., DiCarlo, S. E., Grujic, D., Lowell, B. B., & Dohm, G. L.
(1999).
Regulation of skeletal muscle UCP-2 and UCP-3 gene expression by exercise and denervation. American Journal of Physiology: Endocrinology and Metabolism.
276(1), E217-E221.
-
Cortright, R. N., Zheng, D., Jones, J. P., Fluckey, J. D., DiCarlo, S. E., Grujic, D., Lowell, B. B., & Dohm, G. L.
(1999).
Regulation of skeletal muscle UCP-2 and UCP-3 gene expression by exercise and denervation. American Journal of Physiology: Endocrinology and Metabolism.
276(1 39-1),
-
Cortright, R. N., Zheng, D., Jones, J. P., Fluckey, J. D., DiCarlo, S. E., Grujic, D., Lowell, B. B., & Dohm, G. L.
(1999).
Regulation of skeletal muscle UCP-2 and UCP-3 gene expression by exercise and denervation. AMERICAN JOURNAL OF PHYSIOLOGY.
276(1), E217-E221.
-
Westerlind, K. C., Fluckey, J. D., Gordon, S. E., Kraemer, W. J., Farrell, P. A., & Turner, R. T.
(1998).
Effect of resistance exercise training on cortical and cancellous bone in mature male rats. Journal of Applied Physiology.
84(2), 459-464.
-
Brambrink, J. K., Fluckey, J. D., Hickey, M. S., & Craig, B. W.
(1997).
Influence of muscle mass and work on post-exercise glucose and insulin responses in young untrained subjects. Acta Physiol Scand.
161(3), 371-377.
-
Farrel, P. P., Fluckey, J. D., Vary, T. C., Jefferson, L. S., & Evans, W. J.
(1996).
Effects of age on insulin-stimulated rates of protein synthesis after resistance exercise in rats. The FASEB Journal.
10(3), 112-112.
-
Fluckey, J. D., Vary, T. C., Jefferson, L. S., Evans, W. J., & Farrell, P. A.
(1996).
Insulin stimulation of protein synthesis in rat skeletal muscle following resistance exercise is maintained with advancing age. Journal of Gerontology Series A: Biological Sciences and Medical Sciences.
51(5), B323-B330.
-
Fluckey, J. D., Vary, T. C., Jefferson, L. S., & Farrell, P. A.
(1996).
Augmented insulin action on rates of protein synthesis after resistance exercise in rats. American Journal of Physiology: Endocrinology and Metabolism.
270(2 33-2),
-
Fluckey, J. D., Vary, T. C., Jefferson, L. S., & Farrell, P. A.
(1996).
Augmented insulin action on rates of protein synthesis after resistance exercise in rats. AMERICAN JOURNAL OF PHYSIOLOGY.
270(2 Pt 1), E313-E319.
-
Fluckey, J. D., Vary, T. C., Jefferson, L. S., & Farrell, P. A.
(1996).
Augmented insulin action on rates of protein synthesis after resistance exercise in rats. American Journal of Physiology: Endocrinology and Metabolism.
270(2), E313-E319.
-
Fluckey, J. D., Vary, T. C., Jefferson, L. S., Evans, W. J., & Farrell, P. A.
(1996).
Insulin stimulation of protein synthesis in rat skeletal muscle following resistance exercise is maintained with advancing age. Journal of Gerontology Series A: Biological Sciences and Medical Sciences.
51(5), B323-B330.
-
Fluckey, J. D., Kraemer, W. J., & Farrell, P. A.
(1995).
Pancreatic islet insulin secretion is increased after resistance exercise in rats. Journal of Applied Physiology.
79(4), 1100-1105.
-
Westerlind, K. C., Fluckey, J. D., Gordon, S. E., Kraemer, W. J., Turner, R. T., & Farrell, P. A.
(1995).
EFFECT OF RESISTANCE EXERCISE TRAINING ON CORTICAL AND CANCELLOUS BONE IN RATS: A HISTOMORPHOMETRIC ANALYSIS: 1241. Medicine and Science in Sports and Exercise.
27(5), s221-S221.
-
Fluckey, J. D., Hickey, M. S., Brambrink, J. K., Hart, K. K., Alexander, K., & Craig, B. W.
(1994).
Effects of resistance exercise on glucose tolerance in normal and glucose-intolerant subjects. Journal of Applied Physiology.
77(3), 1087-1092.
-
Fluckey, J. D., Gordon, S. E., Kraemer, W. J., & Fanell, P. A.
(1994).
127 ARGININE STIMULATED INSULIN SECRETION FROM PANCREATIC ISLETS IS INCREASED FOLLOWING RESISTANCE EXERCISE. Medicine and Science in Sports and Exercise.
26(5), s23-S23.
-
Lee, C. W., Galvan, E., Lee, T. V., Chen, V., Bui, S., Crouse, S. F., ... Riechman, S. E.
(2023).
Low Intake of Choline Is Associated with Diminished Strength and Lean Mass Gains in Older Adults. The Journal of Frailty and Aging.
12(1), 78-83.
-
conference paper
-
Uranga, S., O'Reilly, C. L., Lewis, M. H., Lopez, S. M., Nghiem, P. P., & Fluckey, J. D.
(2022).
Anabolic Characterization Of Immortalized Murine L6, And Canine Myok9 Skeletal Myotubes. Medicine and Science in Sports and Exercise.
391-391.
-
Ryan, P. J., Riechman, S., & Fluckey, J. D.
(2022).
Exercise Conditioned Perfusate Slows Growth In Cultured Pancreatic Cancer Cells. Medicine and Science in Sports and Exercise.
606-606.
-
Chen, V. C., Lee, C. W., Fluckey, J. D., & Riechman, S. E.
(2019).
Short Term High Intensity Resistance Exercise-induced Muscle Soreness Is Attenuated with Dietary Cholesterol. Medicine and Science in Sports and Exercise.
868-868.
-
Goodenough, C. G., Davis, A. R., Deaver, J. W., Riechman, S. E., & Fluckey, J. D.
(2019).
mTOR is a Mechanistic Target of Muscle and Cancer Cross-Talk with Exercise. The FASEB Journal.
704.7-704.7.
-
Chen, V., Lee, C. W., Fluckey, J. D., & Riechman, S. E.
(2018).
Blood Lipid is Associated with Skeletal Muscle PPARd Protein Content after a 10-week Resistance Exercise Training. Medicine and Science in Sports and Exercise.
808-808.
-
Lee, C. W., Galvan, E., Lee, T. V., Chen, V., Bui, S., Crouse, S. F., ... Riechman, S. E.
(2018).
The Effects of Choline Intake and Resistance Exercise Training on Strength Gains in Older Adults. Medicine and Science in Sports and Exercise.
82-82.
-
Deaver, J. W., OReilly, C. L., Crouse, S. F., & Fluckey, J. D.
(2017).
Blockade Of Mtor And Erk1/2 Resulted In Attenuated Protein Synthesis Rates In Differentiated C2c12 Myoblasts. Medicine and Science in Sports and Exercise.
500-500.
-
Cardin, J. M., Deaver, J. W., O'Reilly, C. L., Crouse, S. F., & Fluckey, J. D.
(2017).
Characterization of Protein Metabolism in Undifferentiated and Differentiated Murine Muscle Tissue. Medicine and Science in Sports and Exercise.
769-769.
-
Lee, C. W., Galvan, E., Lee, T. V., Chen, V., Bui, S., Crouse, S. F., ... Riechman, S. E.
(2017).
Lower Choline Intake is Associated with Diminished Strength and Lean Mass Gains in Older Adults. Medicine and Science in Sports and Exercise.
321-321.
-
OReilly, C. L., Deaver, J. W., Wiggs, M. P., Lima, F., Swift, J. M., Greene, E. S., Bloomfield, S. A., & Fluckey, J. D.
(2017).
Partial or Complete Unloading of Skeletal Muscle Leads to Specific Alterations of Anabolic Signal Transduction. Medicine and Science in Sports and Exercise.
769-769.
-
Greene, N. P., Lee, D. E., Nilsson, M. I., Washington, T. A., Shimkus, K. L., Perticone, J. I., Crouse, S. F., & Fluckey, J. D.
(2014).
Gene Expression Of Novel Regulators Of Skeletal Muscle Hypertrophy In Obesity: PGC-1 up arrow 4 And Deptor. Medicine and Science in Sports and Exercise.
307-307.
-
Wiggs, M. P., Smuder, A. J., Sollanek, K. J., Shimkus, K. L., Fluckey, J. D., & Powers, S. K.
(2014).
Inhibition of FoxO Signaling Prevents Mechanical Ventilation-Induced Reduction in Protein Synthesis. Medicine and Science in Sports and Exercise.
350-351.
-
Lee, D. E., Fluckey, J. D., Nilsson, M. I., Brown, L. A., Shimkus, K. L., Washington, T. A., Crouse, S. F., & Greene, N. P.
(2014).
Mitochondrial Translation Elongation Limits Mitochondrial Biogenesis In The Obese Response To Resistance Exercise. Medicine and Science in Sports and Exercise.
298-298.
-
Chen, V., Lee, C. W., Lee, T. V., Bui, S., Fluckey, J. D., & Riechman, S. E.
(2013).
Changes in Body Composition with Six Weeks of Resistance Training. The FASEB Journal.
lb759-lb759.
-
Lawler, J. M., Lee, Y., Hord, J. M., Botchlett, R. E., & Fluckey, J. D.
(2013).
Effect of EUK-134 on Insulin Signaling and Morphology Alterations by 7 Days of Hindlimb Unloading in the Rat Soleus. The FASEB Journal.
lb820-lb820.
-
Wiggs, M. P., Hudson, M. B., Smuder, A. J., Nelson, W. B., Shimkus, K. L., Fluckey, J. D., & Powers, S. K.
(2013).
Impact of prolonged mechanical ventilation on diaphragmatic protein synthesis. The FASEB Journal.
lb784-lb784.
-
Bui, S., Shimkus, K. L., Lee, C. W., Lee, T. V., Chen, V., Fluckey, J. D., & Riechman, S. E.
(2013).
The Effect of Caffeine on Protein Synthesis Rates in Rat Gastrocnemius Muscle Tissue. The FASEB Journal.
lb807-lb807.
-
Lee, T. V., Bui, S., Lee, C. W., Chen, V., Fluckey, J. D., & Riechman, S. E.
(2013).
The Effects of Dietary Cholesterol and Resistance Training as Countermeasures to Accelerated Muscle Loss. Medicine and Science in Sports and Exercise.
185-185.
-
Shimkus, K. L., Shirazi-Fard, Y., Hogan, H. A., & Fluckey, J. D.
(2012).
Impact of chronic voluntary resistance training during recovery following hindlimb unloading on rat hindlimb muscles. The FASEB Journal.
1076.4-1076.4.
-
Macias, B. R., Lima, F., Shirazi-Fard, Y., Wiggs, M. P., Fluckey, J. D., Greene, E. S., ... Bloomfield, S. A.
(2011).
Low dose X-ray but not silicon radiation exposure can exacerbate cancellous bone loss during partial weightbearing. BONE.
S175-S175.
-
Ferguson, D. P., Wiggs, M. P., Prabhu, G. S., Fluckey, J. D., & Lightfoot, J. T.
(2011).
The effect of vivo-Morpholinos on Dopamine Receptor 1 (Drd1) and physical activity in mice. The FASEB Journal.
863.1-863.1.
-
Gasier, H. G., Fluckey, J. D., Wiggs, M. P., Lee, C., Previs, S. F., & Reichman, S. E.
(2010).
Acute Resistance Exercise Augments Cumulative Myofibrillar, But Not Mixed Muscle Protein Synthesis. Medicine and Science in Sports and Exercise.
63-64.
-
Nilsson, M. I., Dobson, J. P., Greene, N. P., Cummins, C. B., McHenry, E., Cloud, W. M., ... Fluckey, J. D.
(2010).
Fiber Type-Dependent Suppression of Myocellular Anabolic Response in the Obese Zucker Rat. The FASEB Journal.
806.18-806.18.
-
Wiggs, M. P., Swift, J. M., Lima, F., Greene, E. S., Bloomfield, S. A., & Fluckey, J. D.
(2010).
The effect of simulated 1/6th and 1/3rd gravity on gastrocnemius muscle mass and fractional protein synthesis rates in mice. The FASEB Journal.
616.6-616.6.
-
Gasier, H. G., Wiggs, M. P., Previs, S. F., Riechman, S. E., & Fluckey, J. D.
(2008).
The assessment of in vivo protein synthesis following chronic resistance exercise using (H2O)-H-2. The FASEB Journal.
91-91.
-
Nilsson, M., Swift, J. M., Walthall, C. J., Stallone, J. L., Hogan, H. A., Fluckey, J. D., & Bloomfield, S. A.
(2007).
The effect of resistance exercise on in vivo-derived tomography measures and mechanical properties of rodent bone: Is more load always better?. Journal of Bone and Mineral Research.
S490-S490.
-
Fluckey, J. D., Norrbrand, L., Pozzo, M., Smith, L., & Tesch, P. A.
(2006).
Acute insulin is not necessary for post exercise elevations of muscle protein synthesis after 5 weeks of resistance exercise training. The FASEB Journal.
A821-A821.
-
Carroll, C. C., Fluckey, J. D., Williams, R. H., Sullivan, D. H., & Trappe, T. A.
(2005).
Human soleus and vastus lateralis muscle protein metabolism with an amino acid infusion. The FASEB Journal.
A1119-A1119.
-
Fluckey, J. D., Dupont-Versteegden, E. E., Smith, L., Knox, M., Bennett, P., Gaddy, D., & Peterson, C. A.
(2005).
The capacity of insulin to attenuate rates of protein degradation in rat soleus muscle is maintained after 14 days of hindlimb suspension. The FASEB Journal.
A1125-A1125.
-
Fluckey, J. D., Knox, M., Smith, L., Dupont-Versteegden, E. E., Gaddy, D., Tesch, P. A., & Peterson, C. A.
(2004).
The insulin-facilitated increase of muscle protein synthesis after resistance exercise involves a MAP-kinase pathway. Medicine and Science in Sports and Exercise.
S183-S184.
-
Knox, M., Dupont-Versteegden, E. E., Gaddy, D., Peterson, C. A., & Fluckey, J. D.
(2003).
A novel approach to hind limb suspension in mature rats. The FASEB Journal.
A946-A946.
-
Fluckey, J. D., Tapscott, E. B., Cortright, R. N., Koves, T., Pohnert, S., & Dohm, G. L.
(2003).
Active involvement of PKC for insulin-mediated rates of rat muscle protein synthesis. The FASEB Journal.
A444-A444.
-
Perrien, D. S., Akel, N. S., Montague, D. C., Knox, M., Fluckey, J. D., Dupont-Versteegden, E. E., ... Gaddy, D.
(2003).
Distinct regulation of bone and muscle maintenance during hindlimb suspension by a concentric resistance exercise regimen. Journal of Bone and Mineral Research.
1360-1360.
-
Perrien, D. S., Akel, N. S., Montague, D. C., Knox, M., Fluckey, J. D., Dupont-Versteegden, E. E., ... Gaddy, D.
(2003).
Distinct regulation of bone and muscle maintenance during hindlimb suspension by concentric and eccentric exercise. Journal of Bone and Mineral Research.
S332-S332.
-
Fluckey, J. D., Peterson, C. A., Gaddy-Kurten, D., Knox, M., Smith-Briscoe, L., & Dupont-Versteegden, E.
(2002).
Amino acids derived from proteolysis are preferred for muscle protein synthesis following hindlimb suspension. The FASEB Journal.
A767-A767.
-
Campbell, W. W., Fluckey, J. D., Morse, M. H., & Haub, M. D.
(2002).
Effects of oral pinitol supplementation on oral and intravenous glucose tolerance in older people. The FASEB Journal.
A24-A24.
-
Trappe, T. A., Carrithers, J. A., Trappe, S. W., & Fluckey, J. D.
(2002).
Skeletal muscle myosin and actin content with aging. The FASEB Journal.
A391-A392.
-
Evans, W. J., Trappe, T. A., Fluckey, J. D., & Peterson, C.
(2001).
Exercise and aging: Introduction. International journal of sport nutrition.
S1-S2.
-
Starling, R. D., Liu, X., Fluckey, J. D., Vidal-Puig, A., & Sullivan, D. H.
(2000).
Influence of sibutramine on energy expenditure in African-Americans. Obesity.
89S-89S.
-
Fluckey, J. D., Asp, S., Enevoldsen, L., & Galbo, H.
(2000).
Insulin action on rates of muscle protein synthesis following eccentric, muscle-damaging exercise. JOURNAL OF AGING AND PHYSICAL ACTIVITY.
282-283.
-
Trappe, T. A., Fluckey, J. D., White, F., Lambert, C. P., & Evans, W. J.
(2000).
Skeletal muscle PGF(2 alpha) and PGE(2) in response to eccentric exercise: Influence of ibuprofen and acetaminophen. JOURNAL OF AGING AND PHYSICAL ACTIVITY.
275-276.
-
Stallknecht, B., Donsmark, M., Enevoldsen, L. H., Fluckey, J. D., & Galbo, H.
(1999).
Estimation of rat muscle blood flow by microdialysis probes perfused with ethanol, [C-14]ethanol and (H2O)-H-3. Proceedings of the Nutrition Society.
174A-174A.
-
Fluckey, J. D., Pohnert, S. C., Boyd, S. G., Cortright, R. N., Trappe, T. A., & Dohm, G. L.
(1999).
Insulin stimulation of muscle protein synthesis in obese Zucker rats is not via a rapamycin-sensitive pathway. The FASEB Journal.
A364-A364.
-
Pohnert, S. C., Fluckey, J. D., Lang, M. C., Boyd, S. G., & Dohm, G. L.
(1998).
Effects of thyroid hormone on protein synthesis in rat skeletal muscle. The FASEB Journal.
A430-A430.
-
Fluckey, J. D., Pohnert, S. C., Cortright, R. N., Boyd, S. G., & Dohm, G. L.
(1998).
Obese Zucker rats exhibit insulin sensitivity with respect to rates of protein synthesis. The FASEB Journal.
A430-A430.
-
WESTERLIND, K. C., EVANS, G. E., FLUCKEY, J. D., GORDON, S. E., KRAEMER, W. J., TURNER, R. T., & FARRELL, P. A.
(1995).
THE EFFECT OF RESISTANCE EXERCISE TRAINING ON CORTICAL AND CANCELLOUS BONE IN MATURE RATS. Journal of Bone and Mineral Research.
S351-S351.
-
Uranga, S., O'Reilly, C. L., Lewis, M. H., Lopez, S. M., Nghiem, P. P., & Fluckey, J. D.
(2022).
Anabolic Characterization Of Immortalized Murine L6, And Canine Myok9 Skeletal Myotubes. Medicine and Science in Sports and Exercise.
391-391.
Research
co-principal investigator on
- Upstream Regulation of Nox2 and Skeletal Muscle Atrophy During Microgravity and Countermeasure Development awarded by Ames Research Center - (Mountain View, California, United States) 2019 - 2022
- Pre-Treatment Approaches for Improving the Response of Bone to Disuse and Recovery - awarded by National Aeronautics and Space Administration - (Washington D.C., District of Columbia, United States) 2013 - 2018
- Redox Regulation of Nnos Translocation and Muscle Atrophy During Mechanical Unloading awarded by Ames Research Center - (Mountain View, California, United States) 2012 - 2018
Teaching
teaching activities
- BICH491 Hnr-research Instructor
- KINE386 Sport Physiology Instructor
- KINE433 Physiology Of Exercise Instructor
- KINE435 Phys Of Exercise Lab Instructor
- KINE483 Practicum In Kinesiology Instructor
- KINE485 Directed Studies Instructor
- KINE491 Research Instructor
- KINE629 Physiology Strength Cond Instructor
- KINE637 Exercise Physiology Instructor
- KINE647 Inst & Tech Ex Phys I Instructor
- KINE681 Seminar: Ex Phys Student Instructor
- KINE682 Sem In: Skeletal Muscle Metabo Instructor
- KINE682 Sem In:physiology Of Suprhros Instructor
- KINE683 Practicum In Kinesiology Instructor
- KINE684 Prof Internship Instructor
- KINE684 Prof Internship Instructor
- KINE684 Prof Internship Instructor
- KINE685 Directed Studies Instructor
- KINE685 Directed Studies Instructor
- KINE685 Directed Studies Instructor
- KINE685 Directed Studies: In-ab Instructor
- KINE691 Research Instructor
Works By Students
chaired theses and dissertations
-
Gasier, Heath G. (2009-05). The Effects of Resistance Exercise on In Vivo Cumulative Skeletal Muscle Protein Synthesis.
-
Nilsson, Mats I. (2009-12). Influence of Insulin Resistance on Contractile Activity-Induced Anabolic Response of Skeletal Muscle.
-
Perticone, Jacqueline Ilene (2014-08). Protein Degradative Processes Associated with Anabolic Dysregulation in Diabetic Skeletal Muscle.
-
Wiggs, Michael (2011-08). Simulated Microgravity and Radiation Exposure Effects on the Regulation of Skeletal Muscle Protein Synthesis.
Background
education and training
- Ph.D. in Physiology, Pennsylvania State University - (State College, Pennsylvania, United States) 1995
Contact
first name
- James
has last name
- Fluckey
mailing address
-
Texas A&M University
Health And Kinesiology
4243 TAMU
College Station, TX 77843-4243
USA
Other
- jfluckey@tamu.edu