selected publications academic article Rai, A. K., Carr, J. F., Bautista, D. E., Wang, W., & Mitchell, A. M (2021). ElyC and Cyclic Enterobacterial Common Antigen Regulate Synthesis of Phosphoglyceride-Linked Enterobacterial Common Antigen. mBio. 12(6), e02846-e02821. Bautista, D. E., Carr, J. F., & Mitchell, A. M (2021). Suppressor Mutants: History and Today’s Applications. EcoSal Plus. 9(2), eesp-0037-2020. Grimm, J., Shi, H., Wang, W., Mitchell, A. M., Wingreen, N. S., Huang, K. C., & Silhavy, T. J (2020). The inner membrane protein YhdP modulates the rate of anterograde phospholipid flow in Escherichia coli. Proceedings of the National Academy of Sciences of USA. 117(43), 26907-26914. Rai, A. K., & Mitchell, A. M (2020). Enterobacterial Common Antigen: Synthesis and Function of an Enigmatic Molecule. mBio. 11(4), e01914-e01920. Hart, E. M., Mitchell, A. M., Konovalova, A., Grabowicz, M., Sheng, J., Han, X., ... Silhavy, T. J (2019). A small-molecule inhibitor of BamA impervious to efflux and the outer membrane permeability barrier. Proceedings of the National Academy of Sciences of USA. 116(43), 21748-21757. Mitchell, A. M., & Silhavy, T. J (2019). Envelope stress responses: balancing damage repair and toxicity. Nature Reviews Microbiology. 17(7), 417-428. Silhavy, T. J., & Mitchell, A. M (2019). Genetic Analysis of Protein Translocation. The Protein Journal. 38(3), 217-228. May, K. L., Lehman, K. M., Mitchell, A. M., & Grabowicz, M (2019). A Stress Response Monitoring Lipoprotein Trafficking to the Outer Membrane. mBio. 10(3), e00618-e00619. Mitchell, A. M., Srikumar, T., & Silhavy, T. J (2018). Cyclic Enterobacterial Common Antigen Maintains the Outer Membrane Permeability Barrier of Escherichia coli in a Manner Controlled by YhdP. mBio. 9(4), e01321-e01318. Mitchell, A. M., Wang, W., & Silhavy, T. J (2017). Novel RpoS-Dependent Mechanisms Strengthen the Envelope Permeability Barrier during Stationary Phase. J Bacteriol. 199(2), e00708-e00716. Konovalova, A., Mitchell, A. M., & Silhavy, T. J (2016). A lipoprotein/β-barrel complex monitors lipopolysaccharide integrity transducing information across the outer membrane. Elife. 5, e15276. Xiao, P., Mitchell, A. M., Huang, L. u., Li, C., & Samulski, R. J (2016). Disruption of Microtubules Post-Virus Entry Enhances Adeno-Associated Virus Vector Transduction. HUMAN GENE THERAPY. 27(4), 309-324. Mitchell, A. M., Hirsch, M. L., Li, C., & Samulski, R. J (2014). Promyelocytic leukemia protein is a cell-intrinsic factor inhibiting parvovirus DNA replication. J Virol. 88(2), 925-936. Mitchell, A. M., & Samulski, R. J (2013). Mechanistic insights into the enhancement of adeno-associated virus transduction by proteasome inhibitors. J Virol. 87(23), 13035-13041. Mitchell, A. M., Li, C., & Samulski, R. J (2013). Arsenic trioxide stabilizes accumulations of adeno-associated virus virions at the perinuclear region, increasing transduction in vitro and in vivo. J Virol. 87(8), 4571-4583. Mitchell, A. M., Nicolson, S. C., Warischalk, J. K., & Samulski, R. J (2010). AAV's anatomy: roadmap for optimizing vectors for translational success. Current Gene Therapy. 10(5), 319-340. chapter Mitchell, A. M., Moser, R., Samulski, R. J., & Hirsch, M. L (2016). Stimulation of AAV Gene Editing via DSB Repair. ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY. Advances in Experimental Medicine and Biology. (pp. 125-137). Springer New York. Vance, M. A., Mitchell, A., & Samulski, R. J (2015). AAV Biology, Infectivity and Therapeutic Use from Bench to Clinic. Gene Therapy - Principles and Challenges. InTech. institutional repository document Grimm, J., Shi, H., Wang, W., Mitchell, A. M., Wingreen, N. S., Huang, K. C., & Silhavy, T. J (2020). The inner membrane protein YhdP modulates the rate of anterograde phospholipid flow inEscherichia coli
principal investigator on Elucidating stationary phase changes to the outer membrane permeability barrier awarded by National Institute of General Medical Sciences - (Bethesda, Maryland, United States) 2016 - 2017
teaching activities BIOL406 Bacterial Genetics Instructor BIOL491 Hnr-research Instructor BIOL606 Microbial Genetics Instructor BIOL685 Directed Studies Instructor BIOL691 Research Instructor GENE406 Bacterial Genetics Instructor
education and training Ph.D. in Microbiology and Immunology, University of North Carolina at Chapel Hill - (Chapel Hill, North Carolina, United States) 2013 B.S. in Biotechnology, Elizabethtown College - (Elizabethtown, Pennsylvania, United States) 2008