Probing the metal specificity mechanism of superoxide dismutase from human pathogen Clostridium difficile. uri icon

abstract

  • The molecular mechanism of the metal specificity to superoxide dismutase from human pathogen C. difficile (SODcd) was investigated by X-ray crystallography, spectroscopy, SOD activity assay, electrochemistry, and DFT calculations, and the results indicate that the cognate metal characters tuned by the metal micro-environment dominate the metal specificity of the SODcd.

published proceedings

  • Chem Commun (Camb)

altmetric score

  • 0.5

author list (cited authors)

  • Li, W., Wang, H., Chen, Z., Ye, Q., Tian, Y., Xu, X., ... Tan, X.

citation count

  • 6

complete list of authors

  • Li, Wei||Wang, Hongfei||Chen, Zheng||Ye, Qing||Tian, Yang||Xu, Xin||Huang, Zhongxian||Li, Pingwei||Tan, Xiangshi

publication date

  • January 2014