Sex ratio and natural selection at the human ABO locus.

abstract

• Natural selective effects of ABO maternofetal incompatibility depend on age, sex and gene frequency. This study focuses on differences of fitness according to age and sex. Calculations of genotype frequencies weighted by fitness lead to the hypothesis that forces of natural selection would favor an association of excess males with type O. Studies of polymorphic populations and homogeneous O populations provide empirical support for the hypothesis.

published proceedings

• Hum Hered

author list (cited authors)

• Millard, A. V., & Berlin, E. A.

citation count

• 1

complete list of authors

• Millard, AV||Berlin, EA

publication date

• January 1983

publisher

• Karger Publishers  Publisher

published in

• Human Heredity: international journal of human and medical genetics  Journal

keywords

• Abo Blood-group System
• Female
• Gene Frequency
• Humans
• Male
• Models, Genetic
• Selection, Genetic
• Sex Ratio

PubMed Central ID

• 6862456

Digital Object Identifier (DOI)

• 10.1159/000153363

start page

• 130

end page

• 136

volume

• 33

issue

• 2

URL

• http://dx.doi.org/10.1159/000153363