Chapter 18 Changes in the Endocannabinoid System May Give Insight into new and Effective Treatments for Cancer Chapter uri icon


  • The endocannabinoid system comprises specific cannabinoid receptors such as Cb1 and Cb2, the endogenous ligands (anandamide and 2-arachidonyl glycerol among others) and the proteins responsible for their synthesis and degradation. This system has become the focus of research in recent years because of its potential therapeutic value several disease states. The following review describes our current knowledge of the changes that occur in the endocannabinoid system during carcinogenesis and then focuses on the effects of anandamide on various aspects of the carcinogenic process such as growth, migration, and angiogenesis in tumors from various origins.

author list (cited authors)

  • Alpini, G., & DeMorrow, S.

complete list of authors

  • Alpini, Gianfranco||Demorrow, Sharon

Book Title

  • Vitamins and Hormones

publication date

  • January 2009