Orphan G protein receptor GPR55 as an emerging target in cancer therapy and management Academic Article uri icon

abstract

  • G protein-coupled receptors (GPCRs) modulate a vast array of cellular processes. The current review gives an overview of the general characteristics of GPCRs and their role in physiological conditions. In addition, it describes the current knowledge of the physiological and pathophysiological functions of GPR55, an orphan GPCR, and how it can be exploited as a therapeutic target to combat various cancers.

altmetric score

  • 2.35

author list (cited authors)

  • Leyva-Illades, D., & DeMorrow, S.

citation count

  • 27

publication date

  • July 2013