Demonstration by immunofluorescence that the same cells from chick embryo aortas synthesize elastin and collagen types I and III. Academic Article uri icon

abstract

  • Cells were isolated from the aortas of 17-day old chick embryos and they were stained with fluorescent antibodies specific for Type I collagen, Type I procollagen, Type III collagen, elastin and prolyl hydroxylase. The results indicated that the same cells simultaneously synthesize Type I procollagen, Type III procollagen and elastin. The synthesis of procollagens, and the presence of prolyl hydroxylase, in the same cells which synthesize elastin may well explain why elastin contains hydroxy-proline.

published proceedings

  • Artery

author list (cited authors)

  • Kao, W. W., Gay, S., Bressan, G. M., & Prockop, D. J.

citation count

  • 8

complete list of authors

  • Kao, WW||Gay, S||Bressan, GM||Prockop, DJ

publication date

  • December 1980

published in