Osteogenesis imperfecta. A model for genetic causes of osteoporosis and perhaps several other common diseases of connective tissue. Academic Article

abstract

• Recent studies of patients with the heritable disorder, osteogenesis imperfecta (OI), have demonstrated that a number of OI patients have mutations in one of the two structural genes that code for type I procollagen (1-3). In addition, data we have obtained on one family illustrate how gene analysis can define the genetic component in one form of osteoporosis.

authors

• Prockop, Darwin

published proceedings

• Arthritis Rheum

altmetric score

• 3

author list (cited authors)

• Prockop, D. J.

citation count

• 25

complete list of authors

• Prockop, DJ

publication date

• January 1988

publisher

• Wiley  Publisher

published in

• ARTHRITIS AND RHEUMATISM  Journal

keywords

• Collagen
• Connective Tissue Diseases
• Humans
• Infant
• Male
• Models, Genetic
• Mutation
• Osteogenesis Imperfecta
• Osteoporosis
• Procollagen

PubMed Central ID

• 3345218

Digital Object Identifier (DOI)

• 10.1002/art.1780310101

start page

• 1

end page

• 8

volume

• 31

issue

• 1

URL

• http://dx.doi.org/10.1002/art.1780310101