Defining the risks of mesenchymal stromal cell therapy. Academic Article uri icon

abstract

  • Abstract We address the issue of the potential for malignant transformation of cultured mesenchymal stromal cells (MSC) commonly used in clinical cell-therapy protocols and describe the culture conditions under which tumorigenesis is likely to be an extremely uncommon event.

published proceedings

  • Cytotherapy

altmetric score

  • 14.88

author list (cited authors)

  • Prockop, D. J., Brenner, M., Fibbe, W. E., Horwitz, E., Le Blanc, K., Phinney, D. G., ... Keating, A.

citation count

  • 259

complete list of authors

  • Prockop, Darwin J||Brenner, Malcolm||Fibbe, Willem E||Horwitz, Edwin||Le Blanc, Katarina||Phinney, Donald G||Simmons, Paul J||Sensebe, Luc||Keating, Armand

publication date

  • January 2010