Medical therapies with adult stem/progenitor cells (MSCs): a backward journey from dramatic results in vivo to the cellular and molecular explanations. Academic Article uri icon

abstract

  • There is currently great interest in the use of mesenchymal stem/stromal cells (MSCs) for the therapy of many diseases of animals and humans. However, we are still left with the serious challenges in explaining the beneficial effects of the cells. Hence, it is essential to work backward from dramatic results obtained in vivo to the cellular and molecular explanations in order to discover the secrets of MSCs. This review will focus on recent data that have changed the paradigms for understanding the therapeutic potentials of MSCs.

published proceedings

  • J Cell Biochem

author list (cited authors)

  • Prockop, D. J., & Oh, J. Y.

citation count

  • 97

complete list of authors

  • Prockop, Darwin J||Oh, Joo Youn

publication date

  • May 2012

publisher