Directed evolution of enzymes and pathways for industrial biocatalysis. Academic Article

abstract

• Directed evolution has become a powerful tool for developing enzyme and whole cell based biocatalysts. Significant recent advances include the creation of novel enzyme functions and the development of several new efficient directed evolution methods. The combination of directed evolution and rational design promises to accelerate the development of biocatalysts for applications in the pharmaceutical, chemical and food industries.

authors

• Chen, Zhilei

published proceedings

• Curr Opin Biotechnol

altmetric score

• 3

author list (cited authors)

• Zhao, H., Chockalingam, K., & Chen, Z.

citation count

• 136

complete list of authors

• Zhao, Huimin||Chockalingam, Karuppiah||Chen, Zhilei

publication date

• January 2002

publisher

• Elsevier  Publisher

published in

• Current Opinion in Biotechnology  Journal

keywords

• Catalysis
• Directed Molecular Evolution
• ENZYMES
• Enzyme Stability
• Humans
• Mutagenesis
• Mutagenesis, Site-Directed
• Sensitivity And Specificity

Digital Object Identifier (DOI)

• 10.1016/s0958-1669(02)00291-4

start page

• 104

end page

• 110

volume

• 13

issue

• 2

URL

• http://dx.doi.org/10.1016/s0958-1669(02)00291-4