Imidazole acetic acid as a substitute for cAMP.
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abstract
The ability of imidazole acetic acid (IA) to substitute for cAMP was demonstrated by use of a series of strains carrying a lesion in the cya structural gene. The substitution of IA for cAMP was specific for the L-arabinose operon in that this compound was ineffective in substituting for cAMP in the lactose or maltose catabolic systems. The cAMP receptor protein (CRP) and the araC gene product were necessary for the IA mediated induction of the L-arabinose system. 1979.