Developmentally regulated processing and replication of the Tetrahymena rDNA minichromosome. Academic Article uri icon


  • The ribosomal DNA locus of Tetrahymena thermophila undergoes a dramatic series of developmentally regulated processing events to generate the amplified rDNA minichromosome during formation of the somatic macronucleus. DNA transformation and classical genetic approaches have identified cis-acting elements that regulate rDNA processing in the developing macronucleus and subsequent vegetative rDNA maintenance.

published proceedings

  • Curr Opin Genet Dev

author list (cited authors)

  • Kapler, G. M.

citation count

  • 36

complete list of authors

  • Kapler, GM

publication date

  • October 1993