[The effect of vasoactive factors on the growth of of coronary endothelial cells]. Academic Article

abstract

• The aim of this study was to evaluate the effect of adenosine and bradykinin on endothelial cell growth at capillary level. DNA synthesis was measured in subconfluent capillary endothelial cells obtained from coronary venules (CVEC) after exposure to adenosine or bradykinin. Our results indicate that adenosine and bradykinin induced a dose-dependent proliferation of CVEC. Maximal effect was observed at the dose 100 microM concentration for adenosine and 0.1 microM concentration for bradykinin.

authors

• Meininger, Cynthia

published proceedings

• Cardiologia

author list (cited authors)

• Ziche, M., Parenti, A., Morbidelli, L., Meininger, C. J., Granger, H. J., & Ledda, F.

citation count

• 8

complete list of authors

• Ziche, M||Parenti, A||Morbidelli, L||Meininger, CJ||Granger, HJ||Ledda, F

publication date

• August 1992

published in

• Cardiologia (Rome, Italy)  Journal

keywords

• Adenosine
• Animals
• Bradykinin
• Cattle
• Cell Division
• Cells, Cultured
• Coronary Vessels
• Dose-Response Relationship, Drug
• Endothelium, Vascular

PubMed Central ID

• 1486578

start page

• 573

end page

• 575

volume

• 37

issue

• 8