Sequence homologies near the C-termini of the variable surface glycoproteins of Trypanosoma brucei

abstract

• African trypanosomes evade their mammalian host's immune system by the sequential expression of alternative surface glycoproteins. Comparison of the cDNA sequences of five antigenically distinct surface proteins and the C-terminal amino acid sequences of four additional ones demonstrates that these nine glycoproteins can be classified into two subsets based on C-terminal amino acid homologies that extend 75-105 amino acids into the protein. 1981 Nature Publishing Group.

authors

• Rice-Ficht, Allison

published proceedings

• Nature

author list (cited authors)

• Rice-Ficht, A. C., Chen, K. K., & Donelson, J. E.

citation count

• 116

complete list of authors

• Rice-Ficht, Allison C||Chen, Kenneth K||Donelson, John E

publication date

• November 1981

publisher

• Springer Nature  Publisher

published in

• Nature  Journal

keywords

• 2 Aetiology
• 2.2 Factors Relating To The Physical Environment
• 3 Good Health And Well Being
• Infectious Diseases
• Vector-borne Diseases

Digital Object Identifier (DOI)

• 10.1038/294053a0

start page

• 53

end page

• 57

volume

• 294

issue

• 5836

URL

• http://dx.doi.org/10.1038/294053a0