Circadian rhythms of vasopressin release from individual rat suprachiasmatic explants in vitro. Academic Article

abstract

• A culture system was developed to study intrinsic oscillations within rat suprachiasmatic nuclei for long periods of time. After isolation in static organ cultures, individual rat suprachiasmatic explants released vasopressin in a circadian fashion for at least 4 cycles. This finding suggests that the suprachiasmatic nucleus contains one or more self-sustained circadian oscillators, and that this method of measuring circadian rhythms from individual suprachiasmatic organ cultures may prove to be a valuable model for elucidating the physiology and biochemistry of mammalian circadian pacemakers.

authors

• Earnest, David

published proceedings

• Brain Res

author list (cited authors)

• Earnest, D. J., & Sladek, C. D.

citation count

• 171

complete list of authors

• Earnest, DJ||Sladek, CD

publication date

• January 2010

publisher

• Elsevier  Publisher

published in

• BRAIN RESEARCH  Journal

keywords

• Animals
• Circadian Rhythm
• Darkness
• Kinetics
• Light
• Male
• Organ Culture Techniques
• Rats
• Rats, Inbred Strains
• Suprachiasmatic Nucleus
• Vasopressins

Digital Object Identifier (DOI)

• 10.1016/0006-8993(86)90119-8

start page

• 129

end page

• 133

volume

• 382

issue

• 1