Synthesis and in vitro Efficacy Studies of Silver Carbene Complexes on Biosafety Level 3 Bacteria. Academic Article

abstract

• A series of N-heterocyclic carbene silver complexes have been synthesized and tested against the select group of bio-safety level 3 bacteria Burkholderia pseudomallei, Burkholderia mallei, Bacillus anthracis, methicillin-resistant Staphylococcus aureus and Yersinia pestis. Minimal inhibitory concentrations, minimal bactericidal and killing assays demonstrated the exceptional efficacy of the complexes against these potentially weaponizable pathogens.

authors

• Cannon, Carolyn

published proceedings

• Eur J Inorg Chem

altmetric score

• 3

author list (cited authors)

• Panzner, M. J., Deeraksa, A., Smith, A., Wright, B. D., Hindi, K. M., Kascatan-Nebioglu, A., ... Youngs, W. J.

citation count

• 59

complete list of authors

• Panzner, Matthew J||Deeraksa, Arpaporn||Smith, Alyssa||Wright, Brian D||Hindi, Khadijah M||Kascatan-Nebioglu, Aysegul||Torres, Alfredo G||Judy, Barbara M||Hovis, Christine E||Hilliard, Julia K||Mallett, Rebekah J||Cope, Emily||Estes, D Mark||Cannon, Carolyn L||Leid, Jeff G||Youngs, Wiley J

publication date

• May 2009

publisher

• Wiley  Publisher

published in

• European Journal of Inorganic Chemistry  Journal

keywords

• Antibiotics
• Burkholderia
• Carbenes
• N-Heterocyclic Carbenes
• Nitrogen Heterocycles
• Silver

PubMed Central ID

• 20160993

Digital Object Identifier (DOI)

• 10.1002/ejic.200801159

start page

• 1739

end page

• 1745

volume

• 2009

issue

• 13

URL

• http://dx.doi.org/10.1002/ejic.200801159