Synthesis and in vitro Efficacy Studies of Silver Carbene Complexes on Biosafety Level 3 Bacteria. Academic Article uri icon


  • A series of N-heterocyclic carbene silver complexes have been synthesized and tested against the select group of bio-safety level 3 bacteria Burkholderia pseudomallei, Burkholderia mallei, Bacillus anthracis, methicillin-resistant Staphylococcus aureus and Yersinia pestis. Minimal inhibitory concentrations, minimal bactericidal and killing assays demonstrated the exceptional efficacy of the complexes against these potentially weaponizable pathogens.

published proceedings

  • Eur J Inorg Chem

altmetric score

  • 3

author list (cited authors)

  • Panzner, M. J., Deeraksa, A., Smith, A., Wright, B. D., Hindi, K. M., Kascatan-Nebioglu, A., ... Youngs, W. J.

citation count

  • 59

complete list of authors

  • Panzner, Matthew J||Deeraksa, Arpaporn||Smith, Alyssa||Wright, Brian D||Hindi, Khadijah M||Kascatan-Nebioglu, Aysegul||Torres, Alfredo G||Judy, Barbara M||Hovis, Christine E||Hilliard, Julia K||Mallett, Rebekah J||Cope, Emily||Estes, D Mark||Cannon, Carolyn L||Leid, Jeff G||Youngs, Wiley J

publication date

  • May 2009