The use of 111Ag as a tool for studying biological distribution of silver-based antimicrobials. Academic Article uri icon

abstract

  • Recently, there has been an emergence of significant interest in silver-based antimicrobials. Our goal was to develop a radioactive tracer for investigating the biological fate of such compounds. Purified 111Ag was incorporated into the methylated caffeine analogue, IC1 to yield the silver carbene complex designated as [111Ag]SCC1 and investigated in biodistribution studies.

published proceedings

  • Medchemcomm

author list (cited authors)

  • Aweda, T. A., Ikotun, O., Mastren, T., Cannon, C. L., Wright, B., Youngs, W. J., ... Lapi, S. E.

citation count

  • 12

complete list of authors

  • Aweda, Tolulope A||Ikotun, Oluwatayo||Mastren, Tara||Cannon, Carolyn L||Wright, Brian||Youngs, Wiley J||Cutler, Cathy||Guthrie, James||Lapi, Suzanne E

publication date

  • June 2013