Hypothyroidism and nutritional status alter 3,5,3'-triiodothyronine (T3) receptors in isolated liver nuclei of Anabas testudineus (Bloch). Academic Article

abstract

• T3 receptors are ligand-dependent transcriptional activators that can stimulate gene expression resulting in growth and development. In this study T3 binding sites on isolated liver nuclei are demonstrated in the teleost Anabas testudineus. The effect of hypothyroidism and feeding of polyunsaturated fatty acids (PUFA) on T3 receptor number and binding affinity was also studied. Hypothyroidism caused an increase in T3 receptor number and a decrease in receptor affinity. PUFA feeding also increased the T3 receptor number without any significant change in its receptor affinity.

authors

• Bake, Shameena

published proceedings

• Endocr Res

author list (cited authors)

• Shameena, B., Renuka, T. R., Varghese, S., Paulose, C. S., & Oommen, O. V.

citation count

• 0

complete list of authors

• Shameena, B||Renuka, TR||Varghese, S||Paulose, CS||Oommen, OV

publication date

• January 2001

publisher

• Taylor & Francis  Publisher

published in

• Endocrine Research  Journal

keywords

• Animal Nutritional Physiological Phenomena
• Animals
• Cell Nucleus
• Dietary Fats
• Fatty Acids, Unsaturated
• Female
• Liver
• Perciformes
• Propylthiouracil
• Receptors, Thyroid Hormone
• Thyroid Gland

Digital Object Identifier (DOI)

• 10.1081/erc-100106010

start page

• 329

end page

• 336

volume

• 27

issue

• 3

URL

• http://dx.doi.org/10.1081/erc-100106010