Immunohistochemical localization of cadherin and catenin adhesion molecules in the murine growth plate. Academic Article

abstract

• Mouse tibial growth plates were examined for the presence of adhesion molecules using immunohistochemistry and RT-PCR. All of the components of the classical cadherin/catenin complex (cadherin, alpha-, beta-, and gamma-catenin), as well as a heavy presence of p120, were identified in the murine growth plate. All of the major cadherins (1-5, 11, 13, and 15) were, for the first time, identified and localized in the murine growth plate. We have demonstrated that most of the cadherins and catenins reside in the zone of hypertrophy. Only alpha-catenin and E-, P-, R-, and VE-cadherin were found in all regions of the growth plate. The results for T-cadherin were inconclusive.

authors

• Zimmer, Warren

published proceedings

• J Histochem Cytochem

author list (cited authors)

• Sampson, H. W., Dearman, A. C., Akintola, A. D., Zimmer, W. E., & Parrish, A. R.

citation count

• 10

complete list of authors

• Sampson, H Wayne||Dearman, Alaina C||Akintola, Adebayo D||Zimmer, Warren E||Parrish, Alan R

publication date

• August 2007

publisher

• SAGE Publications  Publisher

published in

• Journal of Histochemistry and Cytochemistry: imaging the spectrum of cell biology  Journal

keywords

• Animals
• Cadherins
• Catenins
• Growth Plate
• Immunohistochemistry
• Mice
• Mice, Inbred C57BL
• Reverse Transcriptase Polymerase Chain Reaction
• Tibia

Digital Object Identifier (DOI)

• 10.1369/jhc.7A7184.2007

start page

• 845

end page

• 852

volume

• 55

issue

• 8

URL

• http://dx.doi.org/10.1369/jhc.7a7184.2007