Disorders of gastrointestinal motility associated with diabetes mellitus.

abstract

• Gastrointestinal symptoms such as vomiting, constipation, diarrhea, and fecal incontinence occur frequently in patients with diabetes mellitus. In a survey of 136 diabetic outpatients, 76% had one or more gastrointestinal symptoms, the commonest symptom being constipation (found in 60%). In many cases these symptoms are thought to be due to abnormal gastrointestinal motility that, in turn, may be a manifestation of diabetic autonomic neuropathy involving the gastrointestinal tract. The pathophysiology of these gastrointestinal symptoms, clarified in recent studies, and the clinical features and treatment of these problems in diabetic patients are reviewed.

authors

• Schiller, Lawrence

published proceedings

• Ann Intern Med

author list (cited authors)

• Feldman, M., & Schiller, L. R.

complete list of authors

• Feldman, M||Schiller, LR

publisher

• American College of Physicians  Publisher

published in

• Annals of Internal Medicine  Journal

keywords

• Autonomic Nervous System Diseases
• Bethanechol Compounds
• Constipation
• Diabetes Complications
• Diabetic Ketoacidosis
• Diabetic Neuropathies
• Diarrhea
• Electrophysiology
• Fecal Incontinence
• Gastric Emptying
• Gastrointestinal Diseases
• Gastrointestinal Motility
• Humans
• Membrane Potentials
• Metoclopramide
• Nausea
• Pain
• Phenothiazines
• Stomach
• Vomiting

PubMed Central ID

• 6402969

Digital Object Identifier (DOI)

• 10.7326/0003-4819-98-3-378

start page

• 378

end page

• 384

volume

• 98

issue

• 3

URL

• https://doi.org/10.7326/0003-4819-98-3-378