Developmental biology of Coxiella burnettii. Academic Article uri icon


  • The obligate intracellular bacterial agent of human Q fever, Coxiella burnetii, has a remarkable ability to persist in the extracellular environment. It replicates only when phagocytosed and delivered to the phagolysosome, where it resists degradation. Different morphological forms of the bacterium have different resistance properties and appear to be stages of a developmental cycle. Despite the lack of genetic systems, the molecular events surrounding C. burnetii development are now being unraveled.

published proceedings

  • Trends Microbiol

author list (cited authors)

  • Heinzen, R. A., Hackstadt, T., & Samuel, J. E.

citation count

  • 146

complete list of authors

  • Heinzen, RA||Hackstadt, T||Samuel, JE

publication date

  • April 1999