Fiber optic microendoscopy for preclinical study of bacterial infection dynamics. Academic Article

abstract

• We explore the use of fiber optic microendoscopy to image and quantify bacterial infection in the skin and lungs using an animal model. The contact probe fiber bundle fluorescence microendoscope has a 4 m resolution, a 750 m field of view, and a 1 mm outer diameter. Subcutaneous and intra-tracheal infections of fluorescent Mycobacterium bovis Bacillus Calmette-Gurin (BCG) bacteria were detected in situ from inocula down to 10(4) and 10(7) colony forming units, respectively.

authors

• Cirillo, Jeffrey
• Maitland, Kristen

published proceedings

• Biomed Opt Express

author list (cited authors)

• Mufti, N., Kong, Y., Cirillo, J. D., & Maitland, K. C.

citation count

• 16

complete list of authors

• Mufti, Nooman||Kong, Ying||Cirillo, Jeffrey D||Maitland, Kristen C

publication date

• April 2011

publisher

• Optica Publishing Group  Publisher

published in

• Biomedical Optics Express  Journal

keywords

• Endoscopic Imaging
• Fiber Optics Imaging
• Imaging Systems
• Medical And Biological Imaging

PubMed Central ID

• 21559125

Digital Object Identifier (DOI)

• 10.1364/BOE.2.001121

start page

• 1121

end page

• 1134

volume

• 2

issue

• 5

URL

• http://dx.doi.org/10.1364/boe.2.001121