Studies of action mechanism of antiglaucoma drugs with a newly developed cat model.
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A variety of ocular hypotensive drugs were tested in a new cat model that allows continuous, simultaneous and instantaneous determinations of aqueous humor (AH) formation and outflow to be made. Aside from pilocarpine, which only increased AH outflow, or acetazolamide and timolol, which only decreased AH formation other adrenergic agents tested decreased both AH formation and AH outflow. These findings are compared with previous results reported in the literature and their significance for glaucoma therapy is discussed. 1980.
author list (cited authors)
Chiou, G. C., Liu, H. K., & Trzeciakowski, J.
complete list of authors
Chiou, GC||Liu, HK||Trzeciakowski, J