Phosphatidylinositol transfer proteins: the long and winding road to physiological function. Academic Article

abstract

• Phosphatidylinositol transfer proteins (PITPs) have historically been thought to help execute lipid-sorting events by transporting phospholipid monomers between membrane bilayers. Recent data, however, indicate unanticipated roles for PITPs in the coordination and/or coupling of phospholipid metabolism with vesicle trafficking and the downregulation of signal-transduction reactions. We are only now beginning to appreciate both the identities of PITP-dependent cellular reactions and the intriguing mechanisms by which PITPs execute their functions in eukaryotic cells.

authors

• Bankaitis, Vytas

published proceedings

• Trends Cell Biol

author list (cited authors)

• Kearns, B. G., Alb, J. G., & Bankaitis, V.

citation count

• 76

complete list of authors

• Kearns, BG||Alb, JG||Bankaitis, V

publication date

• January 1998

publisher

• Elsevier  Publisher

published in

• Trends in Cell Biology  Journal

keywords

• Biological Transport
• Carrier Proteins
• Fungal Proteins
• Membrane Proteins
• Phosphatidylinositols
• Phospholipid Transfer Proteins
• Saccharomyces Cerevisiae
• Saccharomyces Cerevisiae Proteins

Digital Object Identifier (DOI)

• 10.1016/s0962-8924(98)01281-1

start page

• 276

end page

• 282

volume

• 8

issue

• 7

URL

• http://dx.doi.org/10.1016/s0962-8924(98)01281-1