Phosphatidylinositol/phosphatidylcholine transfer proteins in yeast. Academic Article

abstract

• Phosphatidylinositol transfer proteins (PITPs) are now becoming widely recognized as intriguing proteins that participate in the coordination and coupling of phospholipid metabolism with vesicle trafficking, and in the regulation of important signaling cascades. Yet, only in one case is there a large body of evidence that speaks to the precise identities of PITP-dependent cellular reactions, and to the mechanisms by which PITPs execute function in eukaryotic cells. At present, yeast provide the most powerful system for analysis of the physiology of PITP function in vivo, and the mechanism by which this function is carried out. Here, we review the recent progress and remaining questions in the area of PITP function in yeast.

authors

• Bankaitis, Vytas

published proceedings

• Biochim Biophys Acta

author list (cited authors)

• Li, X., Xie, Z., & Bankaitis, V. A.

citation count

• 53

complete list of authors

• Li, X||Xie, Z||Bankaitis, VA

publication date

• June 2000

publisher

• Elsevier  Publisher

published in

• Biochimica et Biophysica Acta: international journal of biochemistry and biophysics  Journal

keywords

• Biological Transport
• Carrier Proteins
• Fungal Proteins
• Membrane Proteins
• Models, Molecular
• Molecular Structure
• Mutation
• Nitrogenous Group Transferases
• Phosphatidylcholines
• Phosphatidylinositols
• Phospholipid Transfer Proteins
• Phosphoric Monoester Hydrolases
• Receptors, Steroid
• Saccharomyces Cerevisiae
• Saccharomyces Cerevisiae Proteins
• Sequence Homology, Amino Acid

Digital Object Identifier (DOI)

• 10.1016/s1388-1981(00)00048-2

start page

• 55

end page

• 71

volume

• 1486

issue

• 1

URL

• http://dx.doi.org/10.1016/s1388-1981(00)00048-2