Evaluation of Antimicrobial Photodynamic Therapy against Streptococcus mutans Biofilm in situ.

abstract

• AIM: This study investigated the effect of antimicrobial photo-dynamic therapy (aPDT) over Streptococcus mutans biofilm. MATERIALS AND METHODS: Eighteen (n = 18) patients were selected and one palatine device with dental blocks was used. The biofilm was treated by curcumin and Photogem with a LED and the effect was analyzed by CFU/ml. RESULTS: Although, statistical analysis showed significant reductions for aPDT mainly with Photogem (p = 0.02), these were low. CONCLUSION: The results suggest a low antimicrobial effect of aPDT over S. mutans biofilm. Some parameters used need to be improved. CLINICAL SIGNIFICANCE: This technique can be a promising in Dentistry.

authors

• Bagnato, Vanderlei

published proceedings

• J Contemp Dent Pract

author list (cited authors)

• Panhca, V. H., Florez, F., Batista de Faria, N., Rastelli, A., Tanomaru, J., Kurachi, C., & Bagnato, V. S.

complete list of authors

• Panhóca, VH||Florez, Fle||Batista de Faria, N||Rastelli, Alessandra Nara de Souza||Tanomaru, Jmg||Kurachi, C||Bagnato, VS

publication date

• March 2016

publisher

• Jaypee Brothers Medical Publishing  Publisher

published in

• Journal of Contemporary Dental Practice  Journal

keywords

• Adolescent
• Biofilm
• Biofilms
• Curcumin
• Dental Caries
• Female
• Hematoporphyrins
• Humans
• Male
• Photochemotherapy
• Photodynamic Therapy
• Photosensitizing Agents
• Randomized Clinical Trial
• Streptococcus Mutans
• Streptococcus Mutans.

PubMed Central ID

• 27207196

Digital Object Identifier (DOI)

• 10.5005/jp-journals-10024-1825

start page

• 184

end page

• 191

volume

• 17

issue

• 3

URL

• http://dx.doi.org/10.5005/jp-journals-10024-1825