Field cancerization treatment using topical photodynamic therapy: A comparison between two aminolevulinate derivatives. Academic Article

abstract

• The objective of this study was to evaluate and compare the clinical response to PDT (Photodynamic Therapy) in field cancerization using two aminolevulinate derivatives. Forty patients with multiple actinic keratosis (AK) on forearms and hands scattered received two sessions of ALA and MAL-PDT at 630nm (36J/cm2). The AK clearance rate was 72 % for both drugs with a significant decrease in AK observed clinically (p<00,001). Clinical improvement in field cancerization using two aminolevulinate derivatives in PDT is proven with no significant difference in the efficacy of drugs.

authors

• Bagnato, Vanderlei

published proceedings

• Photodiagnosis Photodyn Ther

author list (cited authors)

• de Oliveira, E. R., Inada, N. M., Blanco, K. C., Bagnato, V. S., & Salvio, A. G.

complete list of authors

• de Oliveira, Elisangela Ramos||Inada, Natalia M||Blanco, Kate Cristina||Bagnato, Vanderlei S||Salvio, Ana Gabriela

publication date

• June 2020

publisher

• Elsevier  Publisher

published in

• Photodiagnosis and Photodynamic Therapy  Journal

keywords

• 5 - Aminolevulinic Acid
• Actinic Keratosis
• Aminolevulinic Acid
• Humans
• Keratosis, Actinic
• Methyl Aminolevulinate Acid
• Nonmelanoma Cancer
• Photochemotherapy
• Photodynamic Thrapy
• Photosensitizing Agents
• Treatment Outcome

PubMed Central ID

• 31821900

Digital Object Identifier (DOI)

• 10.1016/j.pdpdt.2019.101603

start page

• 101603

end page

• 101603

volume

• 30

URL

• http://dx.doi.org/10.1016/j.pdpdt.2019.101603