Immunocytochemical localization of protein kinase C in resting and activated human neutrophils Academic Article uri icon

abstract

  • An immunocytochemical method was used to determine possible changes in the subcellular distribution of protein kinase C (PKC) in human neutrophils in response to opsonized latex beads and zymosan. While in resting cells most of the PKC immunoreactivity was localized in the cytoplasm, a redistribution of PKC to the plasma and phagosomal membranes was observed in cells treated with latex beads or zymosan for 5-20 min, suggesting a participation of PKC in endocytosis.

author list (cited authors)

  • Deli, E., Kiss, Z., Wilson, E., Lambeth, J. D., & Kuo, J. F.

citation count

  • 16

publication date

  • September 1987

publisher