Differentiation of chiral phosphorus enantiomers by P and H NMR spectroscopy using amino acid derivatives as chemical solvating agents. Academic Article

abstract

• The ability of commercially available amino acid derivatives, especially Fmoc-Trp(Boc)-OH, to differentiate enantiomers of chiral phosphonates, phosphinates, phosphates, phosphine oxides, and phosphonamidates is demonstrated with (31)P, (13)C, and (1)H NMR spectroscopy. The chiral differentiation provided a rapid and convenient method for measuring the enantiomeric purity of these phosphorus compounds.

authors

• Raushel, Frank

published proceedings

• Tetrahedron Asymmetry

author list (cited authors)

• Li, Y., & Raushel, F. M.

citation count

• 23

complete list of authors

• Li, Yingchun||Raushel, Frank M

publication date

• January 2007

publisher

• Elsevier  Publisher

published in

• Tetrahedron: Asymmetry: the international journal for rapid publication on all aspects of asymmetry in organic, inorganic, organometallic, physical and bioorganic chemistry  Journal

keywords

• 0305 Organic Chemistry

Digital Object Identifier (DOI)

• 10.1016/j.tetasy.2007.06.012

start page

• 1391

end page

• 1397

volume

• 18

issue

• 12

URL

• http://dx.doi.org/10.1016/j.tetasy.2007.06.012