Self-cleaning membrane for medical devices Patent uri icon

abstract

  • The disclosure provides a method for cleaning an implanted medical device. In one embodiment, the method includes providing a medical device including a membrane; wherein the membrane comprises a thermoresponsive hydrogel including N-isopropylacrylamide (NIPAAm) or poly(N-isopropylacrylamide) (PNIPAAm), and a volume phase transition temperature (VPTT). The method also includes implanting the medical device into a target area; wherein the membrane temperature is maintained at substantially the same temperature as the target area; wherein temperature fluctuations within the target area that approach, meet and/or exceed the volume phase transition temperature induce deswelling or relative deswelling in the membrane and temperature fluctuations within the target area that are relatively lower and/or approach and/or fall below the volume phase transition temperature induce swelling or relative swelling in the membrane.

author list (cited authors)

  • Grunlan, M. A., Cote, G. L., Abraham, A. A., Fei, R., & Locke, A. K.

complete list of authors

  • Grunlan, Melissa A||Cote, GL||Abraham, AA||Fei, R||Locke, AK

publication date

  • July 2023