A Review of Cutoffs for Nutritional Biomarkers. Academic Article

abstract

• The nutritional status of an individual or population needs to be assessed through valid and reliable biomarkers. Cutoffs generally have an underlying relation to health status and are one of the important quantitative criteria against which biomarker outputs are compared. For this reason, cutoffs are integral for surveys, surveillance, screening, interventions, monitoring, and evaluation. Despite their importance, nutritional biomarker cutoffs have not been adequately addressed in the literature. Furthermore, the field has not reached a consensus on which cutoff to use for each biomarker, and different cutoffs are often used for the same biomarkers in published studies. This review provides a comprehensive overview of cutoffs related to nutritional biomarkers and highlights some of the high-priority research gaps and challenges of using micronutrient case studies.

authors

• Bailey, Regan

published proceedings

• Adv Nutr

altmetric score

• 0.25

author list (cited authors)

• Raghavan, R., Ashour, F. S., & Bailey, R.

citation count

• 48

complete list of authors

• Raghavan, Ramkripa||Ashour, Fayrouz Sakr||Bailey, Regan

publication date

• January 2016

publisher

• Elsevier  Publisher

published in

• Advances in Nutrition  Journal

keywords

• Biomarkers
• Cutoffs
• Humans
• Micronutrients
• Nutrition Assessment
• Nutritional Assessment
• Nutritional Biomarkers
• Nutritional Deficiency
• Nutritional Status
• Nutritional Surveillance
• ROC Curve
• Reference Values
• Youden Index

PubMed Central ID

• 26773019

Digital Object Identifier (DOI)

• 10.3945/an.115.009951

start page

• 112

end page

• 120

volume

• 7

issue

• 1

URL

• http://dx.doi.org/10.3945/an.115.009951