Construction of anatomically correct models of mouse brain networks
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The Mouse Brain Web (MBW), a web-organized database, provides for the construction of anatomically correct models of mouse brain networks. Each web page in this database provides the position, orientation, morphology, and putative synapses for each biologically observed neuron. The MBW has been designed to support (1) mapping of the spatial distribution and morphology of neurons by type; (2) wiring of the network-synaptic assembly; (3) projection of neuron morphology and synapses to geometric multi-compartmental models; (4) search for motifs and basic circuits in the brain networks using customized web-crawlers; and (5) the mapping of anatomically correct networks to physiologically correct network simulations. 2004 Published by Elsevier B.V.