AePUb promoter length modulates gene expression in Aedes aegypti. Academic Article uri icon

abstract

  • Molecular tools for modulating transgene expression in Aedes aegypti are few. Here we demonstrate that adjustments to the AePUb promoter length can alter expression levels of two reporter proteins in Ae. aegypti cell culture and in mosquitoes. This provides a simple means for increasing or decreasing expression of a gene of interest and easy translation from cells to whole insects.

published proceedings

  • Sci Rep

author list (cited authors)

  • Anderson, M., Leftwich, P. T., Wilson, R., Paladino, L., Basu, S., Rooney, S., Adelman, Z. N., & Alphey, L.

complete list of authors

  • Anderson, Michelle AE||Leftwich, Philip T||Wilson, Ray||Paladino, Leonela Z Carabajal||Basu, Sanjay||Rooney, Sara||Adelman, Zach N||Alphey, Luke

publication date

  • November 2023