Recent Advances in Structural Studies of Single-Stranded RNA Bacteriophages Academic Article

abstract

• Positive-sense single-stranded RNA (ssRNA) bacteriophages (phages) were first isolated six decades ago. Since then, extensive research has been conducted on these ssRNA phages, particularly those infecting E. coli. With small genomes of typically 34 kb that usually encode four essential proteins, ssRNA phages employ a straightforward infectious cycle involving host adsorption, genome entry, genome replication, phage assembly, and host lysis. Recent advancements in metagenomics and transcriptomics have led to the identification of ~65,000 sequences from ssRNA phages, expanding our understanding of their prevalence and potential hosts. This review article illuminates significant investigations into ssRNA phages, with a focal point on their structural aspects, providing insights into the various stages of their infectious cycle.

authors

• Zhang, Junjie

published proceedings

• Viruses

author list (cited authors)

• Thongchol, J., Lill, Z., Hoover, Z., & Zhang, J.

complete list of authors

• Thongchol, Jirapat||Lill, Zachary||Hoover, Zachary||Zhang, Junjie

publisher

• MDPI  Publisher

published in

• Viruses  Journal

keywords

• 3 Good Health And Well Being
• 31 Biological Sciences
• 3107 Microbiology
• Genetics
• Human Genome
• Infection

Digital Object Identifier (DOI)

• 10.3390/v15101985

start page

• 1985

end page

• 1985

volume

• 15

issue

• 10

URL

• http://dx.doi.org/10.3390/v15101985