BIOANALYSIS OF POLYCHLORINATED DIBENZOFURAN AND DIBENZO-P-DIOXIN MIXTURES IN FLY-ASH
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The biologic activities of the polychlorinated dibenzofuran and dibenzo-p-dioxin fractions from fly ash extracts are assessed by measuring their potencies as inducers of ethoxyresorufin 0-deethylase and aryl hydrocarbon hydroxylase in rat hepatoma H-4-II E cells and their binding affinities to the cytosolic receptor protein. The utility of these bioassays for the analysis of the toxic halogenated aryl hydrocarbons is discussed. 1983.