Effects of diet type during an exercise and weight loss program on markers of metabolic syndrome in women with elevated uric acid levels
Academic Article
Overview
Research
Identity
Additional Document Info
Other
View All
Overview
abstract
237 women (419 yrs, 1647 cm; 9317 kg; 356 kg/m2) consumed 1,200 kcal/d for 1wk and 1,600 kcal/d for 9 wks consisting of 55% CHO, 15% P, and 30% F (HC, n=76) or 715% CHO, 5563% P, and 30% F (HP, n=161) while participating in a 30min circuit training program 3 d/wk. Blood samples and DEXA body composition measurements were obtained at 0 & 10 wks and analyzed by MANOVA. Subjects were stratified into groups of less than (LU) and higher than (HU) median uric acid (UA) levels (4.8 mg/dl). UA levels were significantly different between groups (LU 3.80.6; HU 5.70.9 mg/dl, p=0.001). Diet and training significantly decreased (p<0.003) body weight (3.63.0 kg), fat mass (2.62.8 kg), waist circumference (2.89 %), total CHL (2.913 %), and SBP (2.112 %). Significant interactions were seen in weight loss (HP 3.94.2; HC 2.83.1 kg, p=0.06), fat loss (HP 3.03.0; HC 1.72.1 kg, p=0.001), waist circumference (HP 3.68; HC 1.311 %, p=0.08), and TG (HP 4.731; HC 5.039 %, p=0.04). Significant diet x UA level x time effects were seen in weight loss (HP/LU 3.24.3, HP/HU 4.64.1, HC/LU 3.73.4, HC/HU 3.93.9, p=0.03), fat loss (HP/LU 2.73.0, HP/HU 3.33.0, HC/LU 2.32.2, HC/HU 1.12.0, p=0.02), and blood glucose (HP/LU 0.419, HP/HU 2.712, HC/LU 1.49, HC/HU 2.611, p=0.08). Results indicate that individuals with higher UA levels may experience greater weight and fat loss following a HP diet during training.
