Assessment of factors related to carbohydrate intolerance II: OGTT glucose at 120 minutes (LB298)
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abstract
The OGTT is a gold standard in assessing carbohydrate intolerance (CI) and insulin resistance. However, the test is costly and time consuming. This study examined whether responses to a carbohydrate intolerance survey (CI) could predict response to an OGTT. 108 women (31.613 yrs, 34.77% body fat, 25.34 kg/m2) donated fasting blood samples, completed a CI inventory, had body composition and health measures determined, and underwent a 75g, 2hr OGTT. Pearson product correlations were performed to determine which factors correlated with OGTT glucose at 120 minutes (G120). Results revealed significant correlations (p<0.05) in G120 (11225 mg/dl) to glucose AUC (r=0.60), glucose AUMC (r=0.73), Cmax (r=0.34), fasting insulin (r=0.34), HOMA (r=0.37), height (r=0.33), resting HR (r=0.29), BMC (r=0.34), BMD (r=0.23), FFM (r=0.39), DEXA body fat (0.24), BIA body fat (r=0.22), and perceptions of being more than 25 lbs overweight (r=0.25). These findings indicate that OGTT G120 is positively correlated to OGTT glucose AUC, fasting insulin, and HOMA. Further, that shorter women who perceive themselves as more than 25 lbs overweight with a higher body fat and resting HR with lower FFM, BMC, and BMD were more related to G120 during a OGTT.Grant Funding Source: Supported by Curves International (Waco, TX)
