Spatial landscape of the tumor immune microenvironment. Academic Article

abstract

• Two recent studies published in Nature by Karimi et al. and Sorin et al. applied multiplexed imaging mass cytometry (IMC) to characterize the single-cell tumor immune landscapes covering millions of cells in brain tumors and lung adenocarcinomas (LUAD). They identified specific cell subtypes and cell-cell interactions that correlate with distinct clinical outcomes, thus providing valuable insights into tumor biology and prognostic prediction based on spatial architecture.

published proceedings

• Trends Cancer

altmetric score

• 4.85

author list (cited authors)

• Chen, Y., Liu, Y., & Han, L.

citation count

• 0

complete list of authors

• Chen, Yamei||Liu, Yuan||Han, Leng

publication date

• June 2023

publisher

• Elsevier  Publisher

published in

• n2405-8025ISSN  Journal

keywords

• Adenocarcinoma Of Lung
• Brain Neoplasms
• Cell Communication
• Clinical Outcome
• Humans
• Lung Neoplasms
• Single-cell
• Spatial Omics
• Tumor Microenvironment

PubMed Central ID

• 36967255

Digital Object Identifier (DOI)

• 10.1016/j.trecan.2023.03.006

start page

• 459

end page

• 460

volume

• 9

issue

• 6

URL

• http://dx.doi.org/10.1016/j.trecan.2023.03.006