Spatial landscape of the tumor immune microenvironment. Academic Article uri icon

abstract

  • Two recent studies published in Nature by Karimi et al. and Sorin et al. applied multiplexed imaging mass cytometry (IMC) to characterize the single-cell tumor immune landscapes covering millions of cells in brain tumors and lung adenocarcinomas (LUAD). They identified specific cell subtypes and cell-cell interactions that correlate with distinct clinical outcomes, thus providing valuable insights into tumor biology and prognostic prediction based on spatial architecture.

published proceedings

  • Trends Cancer

author list (cited authors)

  • Chen, Y., Liu, Y., & Han, L.

complete list of authors

  • Chen, Yamei||Liu, Yuan||Han, Leng

publication date

  • June 2023