PiRNA-like RNAs in the marsupial Monodelphis domestica identify transcription clusters and likely marsupial transposon targets. Academic Article

abstract

• PIWI-interacting RNAs (piRNAs) are a recently discovered class of small noncoding RNAs that have been detected in human, mouse, rat, zebrafish, and Drosophila genomes. We have utilized a size-directed small-RNA cloning procedure to clone and map more than 300 candidate piRNA-like small RNAs in the genome of the marsupial species Monodelphis domestica. Our results are consistent with those from other species in that the piRNA-like candidate sequences range in size from 28 to 31 nucleotides, show a pronounced preference for uridine at the 5' end, are transcribed from a few large clusters, appear to target transposons, and display virtually no sequence conservation.

authors

• Samollow, Paul

published proceedings

• Mamm Genome

author list (cited authors)

• Devor, E. J., Huang, L., & Samollow, P. B.

citation count

• 8

complete list of authors

• Devor, Eric J||Huang, Lingyan||Samollow, Paul B

publication date

• January 2008

publisher

• Springer Nature  Publisher

published in

• MAMMALIAN GENOME  Journal

keywords

• Animals
• Base Sequence
• Clone Cells
• DNA Transposable Elements
• Male
• Molecular Sequence Data
• Monodelphis
• Multigene Family
• RNA, Small Interfering
• Software
• Transcription, Genetic

Digital Object Identifier (DOI)

• 10.1007/s00335-008-9109-x

start page

• 581

end page

• 586

volume

• 19

issue

• 7-8