Marsupial-specific microRNAs evolved from marsupial-specific transposable elements. Academic Article

abstract

• Using a direct miRNA cloning strategy we previously identified fourteen marsupial- or species-specific microRNAs in the marsupial species Monodelphis domestica. In the present study we examined each of the pre-miRNAs and their flanking sequences and demonstrate that half of these miRNAs evolved from marsupial-specific transposable elements. These findings reinforce the view that transposable elements are a previously unappreciated source of new, lineage-specific microRNAs.

authors

• Samollow, Paul

published proceedings

• Gene

author list (cited authors)

• Devor, E. J., Peek, A. S., Lanier, W., & Samollow, P. B.

citation count

• 35

complete list of authors

• Devor, Eric J||Peek, Andrew S||Lanier, William||Samollow, Paul B

publication date

• January 2009

publisher

• Elsevier  Publisher

published in

• Gene  Journal

keywords

• Animals
• Base Sequence
• DNA Transposable Elements
• Evolution, Molecular
• Genetic Variation
• Male
• Marsupialia
• MicroRNAs
• Molecular Sequence Data
• Nucleic Acid Conformation
• Phylogeny
• Sequence Homology, Nucleic Acid
• Species Specificity

Digital Object Identifier (DOI)

• 10.1016/j.gene.2009.06.019

start page

• 187

end page

• 191

volume

• 448

issue

• 2

URL

• http://dx.doi.org/10.1016/j.gene.2009.06.019