Marsupial-specific microRNAs evolved from marsupial-specific transposable elements Academic Article uri icon

abstract

  • Using a direct miRNA cloning strategy we previously identified fourteen marsupial- or species-specific microRNAs in the marsupial species Monodelphis domestica. In the present study we examined each of the pre-miRNAs and their flanking sequences and demonstrate that half of these miRNAs evolved from marsupial-specific transposable elements. These findings reinforce the view that transposable elements are a previously unappreciated source of new, lineage-specific microRNAs.

author list (cited authors)

  • Devor, E. J., Peek, A. S., Lanier, W., & Samollow, P. B.

citation count

  • 35

publication date

  • December 2009

published in