Case of Extensively Drug-Resistant Shigella sonnei Infection, United States.

abstract

• We report extensively drug-resistant (XDR) Shigella sonnei infection in an immunocompromised patient in Texas, USA. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry failed to identify XDR Shigella, but whole-genome sequencing accurately characterized the strain. First-line antimicrobials are not effective against emerging XDR Shigella. Fosfomycin, carbapenems, and tigecycline are potential alternatives.

authors

• Jinadatha, Chetan

published proceedings

• Emerg Infect Dis

author list (cited authors)

• Choi, H., Navarathna, D. H., Harston, B. L., Hwang, M., Corona, B., San Juan, M. R., & Jinadatha, C.

complete list of authors

• Choi, Hosoon||Navarathna, Dhammika H||Harston, Brennon L||Hwang, Munok||Corona, Brandon||San Juan, Ma Rowen||Jinadatha, Chetan

publication date

• August 2023

publisher

• Centers for Disease Control and Prevention (CDC)  Publisher

published in

• Emerging Infectious Diseases  Journal

keywords

• Anti-Bacterial Agents
• Anti-Infective Agents
• Antimicrobial Resistance
• Bacteria
• Dysentery, Bacillary
• Enteric Infections
• Extensively Drug-resistant Shigella
• Humans
• Men Who Have Sex With Men
• Microbial Sensitivity Tests
• Msm
• Sexually Transmitted Infections
• Shigella
• Shigella Sonnei
• United States
• Whole-genome Sequencing
• Xdr Shigella

PubMed Central ID

• 37486233

Digital Object Identifier (DOI)

• 10.3201/eid2908.230411

start page

• 1708

end page

• 1711

volume

• 29

issue

• 8

URL

• https://doi.org/10.3201/eid2908.230411