Analysis of neuraminidase isozyme phenotypes in mammalian tissues: an electrophoretic approach. Academic Article

abstract

• A simple cellulose acetate electrophoretic method for visualizing mammalian neuraminidase isozymes has been developed. Application of the method with rat and mouse liver extracts reveals the presence of two distinct isozymes in each species. Each isozyme exhibits tremendous variation in activity between inbred strains. The two isozymes vary independently of one another suggesting that their activities are controlled by different genes. The neuraminidase phenotypes detected in these inbred strains via electrophoresis are consistent with published accounts of neuraminidase phenotypes determined fluorometrically in whole liver homogenates, but also indicate the presence of a second isozyme not perceived by this other procedure.

authors

• Samollow, Paul

published proceedings

• Biochem Biophys Res Commun

author list (cited authors)

• Samollow, P. B., VandeBerg, J. L., Kunz, H. W., & Gill, T. J.

citation count

• 9

complete list of authors

• Samollow, PB||VandeBerg, JL||Kunz, HW||Gill, TJ

publication date

• January 1985

publisher

• Elsevier  Publisher

published in

• Biochemical and Biophysical Research Communications  Journal

keywords

• Animals
• Electrophoresis, Cellulose Acetate
• Isoenzymes
• Liver
• Mice
• Mice, Inbred Strains
• Neuraminidase
• Phenotype
• Rats
• Rats, Inbred Strains
• Species Specificity

Digital Object Identifier (DOI)

• 10.1016/0006-291x(85)90310-9

start page

• 1182

end page

• 1188

volume

• 126

issue

• 3

URL

• http://dx.doi.org/10.1016/0006-291x(85)90310-9