Development of a linkage map and QTL scan for growth traits in North American bison. Academic Article

abstract

• PCR protocols incorporating fluorescently labeled multiplexed primer combinations were developed to produce a linkage map for bison. Three hundred fifty eight microsatellite loci spanning all 29 autosomes were genotyped via 83 PCR multiplexes and nine individual amplifications. A total of 292 markers were integrated into an autosomal linkage map for bison. The sex averaged bison map (2,647 cM) was approximately 9% longer than the corresponding USDA MARC map, which covered 2,415 cM. Utilizing weaning, yearling and 17-month weights from two private bison herds, a QTL scan was conducted using the developed linkage map. LOD peaks suggestive of QTL were identified on chromosomes 2, 7, 15, and 24 for weaning weight, chromosomes 4, 14, and 15 for yearling weight and chromosomes 8, 14, and 25 for 17-month weight. Four of the identified chromosomes have conserved synteny with regions harboring growth QTL in cattle.

authors

• Derr, James

published proceedings

• Cytogenet Genome Res

author list (cited authors)

• Schnabel, R. D., Taylor, J. F., & Derr, J. N.

citation count

• 8

complete list of authors

• Schnabel, RD||Taylor, JF||Derr, JN

publication date

• December 2003

publisher

• Karger Publishers  Publisher

published in

• Cytogenetic and Genome Research  Journal

keywords

• Animals
• Bison
• Cattle
• Chromosome Mapping
• Chromosomes
• Female
• Genetic Linkage
• Lod Score
• Male
• Microsatellite Repeats
• Models, Genetic
• Quantitative Trait Loci
• Sex Distribution

PubMed Central ID

• 14970680

Digital Object Identifier (DOI)

• 10.1159/000075726

start page

• 59

end page

• 64

volume

• 102

issue

• 1-4

URL

• http://dx.doi.org/10.1159/000075726