Social stress alters the severity of an animal model of multiple sclerosis Chapter

abstract

• Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS) and a leading cause of disability among young adults (Anderson et al., 1992; Jacobson et al., 1997; Noonan et al., 2002; Sorpedra and Martin, 2005). Common symptoms include loss of motor control or sensation in the limbs, loss of bowel or bladder control, neuropathic pain, optic neuritis, sexual dysfunction, and cognitive dysfunction. The etiology of MS remains uncertain; however, considerable evidence suggests that environmental factors interact with genetic factors to cause disease (Kurtzke and Hyllested, 1987; Noseworthy et al., 2000; Sospedra and Martin, 2005). Suspected environmental factors include viral infection and stress. 2006 Springer Science+Business Media, LLC.

authors

• Meagher, Mary
• Welsh, Christabel Jane

author list (cited authors)

• Meagher, M. W., Johnson, R. R., Good, E., & Welsh, C. J.

citation count

• 2

complete list of authors

• Meagher, Mary W||Johnson, Robin R||Good, Elisabeth||Welsh, C Jane

Book Title

• Neural and Neuroendocrine Mechanisms in Host Defense and Autoimmunity

publication date

• January 2006

publisher

• Springer Nature  Publisher

keywords

• 2 Aetiology
• 2.1 Biological And Endogenous Factors
• 2.2 Factors Relating To The Physical Environment
• Autoimmune Disease
• Behavioral And Social Science
• Brain Disorders
• Chronic Pain
• Clinical Research
• Genetics
• Multiple Sclerosis
• Neurodegenerative
• Neurological
• Neurosciences
• Pain Research
• Pediatric
• Peripheral Neuropathy

Digital Object Identifier (DOI)

• 10.1007/978-0-387-48334-4_11

International Standard Book Number (ISBN) 10

• 0-387-31411-3

International Standard Book Number (ISBN) 13

• 9780387314112

start page

• 216

end page

• 240

URL

• http://dx.doi.org/10.1007/978-0-387-48334-4_11