RASA contains a polymorphic microsatellite and maps to bovine syntenic group U22 on chromosome 7q2.4-qter. Academic Article uri icon

abstract

  • The bovine gene for the p21ras protein activator (RASA) includes in its 5' untranslated region a (TG)n repeat. Analysis of this (TG)n repeat by PCR amplification of genomic DNA revealed a four-allele polymorphism. A cDNA probe was used to assign RASA to the region 2.4-qter of bovine Chromosome (Chr) 7 by in situ hybridization. PCR analysis of a panel of somatic hybrid lines allowed the assignment of RASA to the unassigned syntenic group 22 (U22) and thus localizes U22 on Chr 7.

published proceedings

  • Mamm Genome

author list (cited authors)

  • Eggen, A., Solinas-Toldo, S., Dietz, A. B., Womack, J. E., Stranzinger, G., & Fries, R.

citation count

  • 12

publication date

  • October 1992