The thyroglobulin gene is syntenic with the MYC and MOS protooncogenes and carbonic anhydrase II and maps to chromosome 14 in cattle. Academic Article

abstract

• Using a panel of bovine x Chinese hamster hybrid somatic cells, sequences homologous to genes spanning human chromosome arm 8q have been syntenically assigned in cattle. Thyroglobulin (TG), carbonic anhydrase II (CA2), and the protooncogenes MYC and MOS were assigned to a newly identified bovine syntenic group, U23. Additionally, in situ hybridization of the thyroglobulin probe to bovine metaphase chromosomes revealed this syntenic group to be on bovine chromosome 14 and the bovine thyroglobulin gene to reside at 14q12----q15.

authors

• Threadgill, David
• Womack, James

published proceedings

• Cytogenet Cell Genet

author list (cited authors)

• Threadgill, D. W., Fries, R., Faber, L. K., Vassart, G., Gunawardana, A., Stranzinger, G., & Womack, J. E.

citation count

• 20

complete list of authors

• Threadgill, DW||Fries, R||Faber, LK||Vassart, G||Gunawardana, A||Stranzinger, G||Womack, JE

publication date

• January 1990

publisher

• Karger Publishers  Publisher

published in

• Cytogenetic and Genome Research  Journal

keywords

• Animals
• Autoradiography
• Blotting, Southern
• Carbonic Anhydrases
• Cattle
• Chromosome Mapping
• Cricetinae
• Hybrid Cells
• Nucleic Acid Hybridization
• Proto-Oncogene Proteins
• Proto-Oncogene Proteins C-myc
• Proto-Oncogenes
• Thyroglobulin

PubMed Central ID

• 2108842

Digital Object Identifier (DOI)

• 10.1159/000132890

start page

• 32

end page

• 36

volume

• 53

issue

• 1

URL

• http://dx.doi.org/10.1159/000132890