Orotic acid excretion in some wild-type strains of Escherichia coli K-12. Academic Article uri icon


  • During rapid growth, the excretion of pyrimidines, predominantly uracil, is a common phenomenon in procaryotes and eucaryotes. In Escherichia coli, some K-12 strains excrete orotic acid and not uracil. This is caused by a mutation in the pyrF gene.

published proceedings

  • J Bacteriol

altmetric score

  • 6

author list (cited authors)

  • Womack, J. E., & O'Donovan, G. A.

citation count

  • 15

complete list of authors

  • Womack, JE||O'Donovan, GA

publication date

  • November 1978