Parallel RH mapping of BTA1 with HSA3 and HSA21. Academic Article

abstract

• The development of radiation hybrid (RH) panels has elevated comparative gene mapping to a new level of resolution. In this study, we have constructed parallel RH maps defining rearrangements of gene order within conserved segments of bovine Chromosome (Chr) 1 (BTA1) and human Chrs 3 and 21 (HSA3, HSA21). Six new markers, including one gene, have been added to the bovine map, and 11 human genes were ordered with the human G3 panel. BTA1 is clearly a composite of genetic material conserved on these two human chromosomes with HSA21 homologs at each end of BTA1 flanking a large segment homologous to HSA3. Each of the three conserved segments of BTA1 contains rearrangements of gene order relative to their human counterparts.

authors

• Womack, James

published proceedings

• Mamm Genome

author list (cited authors)

• Rexroad, C. E., & Womack, J. E.

citation count

• 11

complete list of authors

• Rexroad, CE||Womack, JE

publication date

• November 1999

publisher

• Springer Nature  Publisher

published in

• MAMMALIAN GENOME  Journal

keywords

• Animals
• Cattle
• Chromosome Mapping
• Chromosomes, Human, Pair 21
• Chromosomes, Human, Pair 3
• Genetic Markers
• Humans
• Hybrid Cells

PubMed Central ID

• 10556430

Digital Object Identifier (DOI)

• 10.1007/s003359901168

start page

• 1095

end page

• 1097

volume

• 10

issue

• 11

URL

• http://dx.doi.org/10.1007/s003359901168